Playoff Series Breakdown
| First Round Playoff: Angels @ White Sox | ||
| 1 | White Sox 7, Angels 0 | WP: Greinke LP: Kennedy |
| White Sox Win Series 1-0 | ||
| First Round Playoff: Nationals @ Pirates | ||
| 1 | Nationals 5, Pirates 4 | WP: Detwiler LP: Prior |
| Nationals Win Series 1-0 | ||
| Second Round Playoff: White Sox @ Mariners | ||
| 1 | Mariners 5, White Sox 4 | WP: Cameron LP: Feldman |
| 2 | Mariners 7, White Sox 0 | WP: Beckett LP: Arroyo |
| 3 | Mariners 4, White Sox 0 | WP: Riley LP: Kawakami |
| Mariners Win Series 3-0 | ||
| Second Round Playoff: Nationals @ Padres | ||
| 1 | Padres 10, Nationals 1 | WP: Peavy LP: Myette |
| 2 | Padres 5, Nationals 3 | WP: Verlander LP: Peralta |
| 3 | Padres 4, Nationals 0 | WP: Halladay LP: Correia |
| Padres Win Series 3-0 | ||
| Second Round Playoff: Marlins @ Brewers | ||
| 1 | Marlins 10, Brewers 8 | WP: Kazmir LP: Haren |
| 2 | Marlins 6, Brewers 5 | WP: Baez LP: Soria |
| 3 | Marlins 6, Brewers 1 | WP: Myers LP: Jennings |
| Marlins Win Series 3-0 | ||
| Second Round Playoff: Rays @ Tigers | ||
| 1 | Tigers 11, Rays 1 | WP: Campillo LP: Astacio |
| 2 | Rays 5, Tigers 2 | WP: McGowan LP: Hughes |
| 3 | Tigers 6, Rays 0 | WP: Young LP: Gonzalez |
| 4 | Tigers 4, Rays 3 | WP: Burres LP: Astacio |
| Tigers Win Series 3-1 | ||
| Third Round Playoff: Tigers @ Mariners | ||
| 1 | Tigers 11, Mariners 6 | WP: Estrada LP: Brazelton |
| 2 | Mariners 5, Tigers 3 | WP: Beckett LP: Hughes |
| 3 | Tigers 10, Mariners 3 | WP: Young LP: Riley |
| 4 | Mariners 14, Tigers 5 | WP: Vargas LP: Burres |
| 5 | Tigers 2, Mariners 0 | WP: Garland LP: Misch |
| 6 | Mariners 10, Tigers 1 | WP: Brazelton LP: Campillo |
| 7 | Mariners 6, Tigers 0 | WP: Beckett LP: Hughes |
| Mariners Win Series 4-3 | ||
| Third Round Playoff: Marlins @ Padres | ||
| 1 | Padres 5, Marlins 3 | WP: Peavy LP: Quintana |
| 2 | Marlins 12, Padres 1 | WP: Stammen LP: Verlander |
| 3 | Padres 6, Marlins 4 | WP: Halladay LP: Myers |
| 4 | Marlins 3, Padres 2 | WP: Collmenter LP: Volstad |
| 5 | Marlins 6, Padres 3 | WP: Kelly LP: Wheeler |
| 6 | Marlins 5, Padres 3 | WP: Quintana LP: Peavy |
| Marlins Win Series 4-2 | ||
| World Series: Marlins @ Mariners | ||
| 1 | Mariners 4, Marlins 2 | WP: Riley LP: Stammen |
| 2 | Marlins 13, Mariners 3 | WP: Myers LP: Vargas |
| 3 | Marlins 8, Mariners 4 | WP: Axford LP: Brazelton |
| 4 | Mariners 5, Marlins 3 | WP: Beckett LP: Collmenter |
| 5 | Marlins 5, Mariners 4 | WP: Backe LP: Misch |
| 6 | Mariners 11, Marlins 5 | WP: Riley LP: Stammen |
| 7 | Marlins @ Mariners | |
| Series Tied 3-3 | ||
