| SP | Sabathia, C.Sabathia, CC # | 34 | Cubs | L | 100 | 29 | 29 | 19 | 4 | 3.34 | .278 | 1.13 | 8.2 | 2.0 | 7.8 | 207.1 | 189 | 86 | 77 | 25 | 46 | 179 | 13 | 0 | 0 | 2 | 19 | 4 | 2 | 3.57 |
| SP | Verlander, J.Verlander, Justin # | 31 | Mets | R | 95 | 28 | 28 | 14 | 9 | 2.95 | .267 | 1.07 | 7.3 | 2.3 | 7.1 | 207.1 | 168 | 71 | 68 | 19 | 53 | 164 | 3 | 0 | 0 | 1 | 21 | 5 | 1 | 3.45 |
| SP | Vogelsong, R.Vogelsong, Ryan | 30 | Pirates | R | 97 | 27 | 27 | 14 | 6 | 3.26 | .262 | 1.03 | 7.1 | 2.1 | 7.5 | 198.2 | 157 | 75 | 72 | 28 | 47 | 165 | 11 | 0 | 0 | 2 | 14 | 8 | 0 | 4.01 |
| CL | Tazawa, J.Tazawa, Junichi | 28 | Cardinals | R | 97 | 51 | 0 | 2 | 2 | 2.67 | .257 | 1.02 | 6.5 | 2.9 | 10.8 | 60.2 | 43 | 19 | 18 | 6 | 19 | 72 | 0 | 28 | 1 | 0 | 0 | 1 | 0 | 2.90 |
| CL | Bastardo, A.Bastardo, Antonio | 29 | Dodgers | L | 100 | 51 | 0 | 6 | 5 | 2.90 | .275 | 1.10 | 5.9 | 4.0 | 9.8 | 59.0 | 39 | 19 | 19 | 6 | 26 | 64 | 0 | 27 | 4 | 0 | 0 | 2 | 4 | 3.58 |