| SP | Sabathia, C.Sabathia, CC # | 34 | Cubs | L | 100 | 22 | 22 | 15 | 3 | 3.07 | .268 | 1.08 | 7.9 | 1.8 | 7.8 | 161.1 | 141 | 60 | 55 | 16 | 33 | 139 | 11 | 0 | 0 | 1 | 16 | 3 | 2 | 3.24 |
| SP | Verlander, J.Verlander, Justin # | 31 | Mets | R | 95 | 21 | 21 | 11 | 7 | 3.00 | .259 | 1.03 | 7.6 | 1.7 | 7.2 | 156.0 | 131 | 54 | 52 | 15 | 30 | 125 | 3 | 0 | 0 | 1 | 15 | 3 | 1 | 3.28 |
| SP | Vogelsong, R.Vogelsong, Ryan | 30 | Pirates | R | 97 | 20 | 20 | 10 | 5 | 2.77 | .246 | 0.94 | 6.3 | 2.2 | 7.2 | 159.0 | 112 | 52 | 49 | 20 | 38 | 128 | 9 | 0 | 0 | 2 | 12 | 6 | 0 | 3.86 |
| CL | Tazawa, J.Tazawa, Junichi | 28 | Cardinals | R | 97 | 37 | 0 | 2 | 1 | 1.38 | .213 | 0.79 | 5.2 | 2.0 | 10.2 | 45.2 | 26 | 7 | 7 | 4 | 10 | 51 | 0 | 22 | 0 | 0 | 0 | 1 | 0 | 2.62 |
| CL | Bastardo, A.Bastardo, Antonio | 29 | Dodgers | L | 100 | 41 | 0 | 6 | 5 | 3.11 | .284 | 1.14 | 6.5 | 3.9 | 10.2 | 46.1 | 33 | 16 | 16 | 6 | 20 | 52 | 0 | 21 | 3 | 0 | 0 | 2 | 2 | 3.87 |