| SP | Sabathia, C.Sabathia, CC # | 34 | Cubs | L | 100 | 23 | 23 | 15 | 3 | 3.26 | .272 | 1.10 | 8.1 | 1.9 | 8.0 | 165.2 | 148 | 65 | 60 | 17 | 35 | 147 | 11 | 0 | 0 | 1 | 16 | 3 | 2 | 3.25 |
| SP | Verlander, J.Verlander, Justin # | 31 | Mets | R | 95 | 22 | 22 | 11 | 7 | 2.91 | .253 | 1.00 | 7.3 | 1.7 | 7.4 | 164.0 | 133 | 55 | 53 | 15 | 31 | 134 | 3 | 0 | 0 | 1 | 16 | 3 | 1 | 3.18 |
| SP | Vogelsong, R.Vogelsong, Ryan | 30 | Pirates | R | 97 | 21 | 21 | 11 | 5 | 2.89 | .248 | 0.95 | 6.4 | 2.1 | 7.3 | 165.0 | 118 | 56 | 53 | 22 | 39 | 134 | 9 | 0 | 0 | 2 | 12 | 6 | 0 | 3.93 |
| CL | Tazawa, J.Tazawa, Junichi | 28 | Cardinals | R | 97 | 40 | 0 | 2 | 1 | 1.29 | .219 | 0.82 | 5.3 | 2.3 | 10.9 | 48.2 | 28 | 8 | 7 | 4 | 12 | 58 | 0 | 23 | 0 | 0 | 0 | 1 | 0 | 2.48 |
| CL | Bastardo, A.Bastardo, Antonio | 29 | Dodgers | L | 100 | 42 | 0 | 6 | 5 | 3.04 | .283 | 1.14 | 6.5 | 3.8 | 10.0 | 47.1 | 34 | 16 | 16 | 6 | 20 | 52 | 0 | 22 | 3 | 0 | 0 | 2 | 2 | 3.85 |