| SP | Peavy, J.Peavy, Jake † # $ | Mariners | R | 127.0 | 29 | 29 | 17 | 3 | 3.67 | .276 | 1.13 | 8.1 | 2.0 | 7.1 | 201.0 | 182 | 84 | 82 | 24 | 45 | 159 | 4 | 0 | 0 | 2 | 17 | 3 | 3 | 3.69 |
| CL | Feldman, S.Feldman, Scott † $$ | White Sox | R | 112.5 | 59 | 0 | 7 | 5 | 2.87 | .264 | 1.06 | 7.1 | 2.5 | 10.9 | 75.1 | 59 | 25 | 24 | 9 | 21 | 91 | 0 | 27 | 4 | 0 | 0 | 1 | 0 | 3.01 |
| SP | Leake, M.Leake, Mike † $$ | Rangers | R | 109.0 | 28 | 28 | 16 | 11 | 3.40 | .284 | 1.17 | 8.5 | 2.0 | 6.7 | 201.1 | 190 | 84 | 76 | 27 | 45 | 149 | 3 | 0 | 0 | 1 | 18 | 4 | 1 | 4.00 |
| SP | Claussen, B.Claussen, Brandon † $$ | Blue Jays | L | 107.0 | 29 | 29 | 17 | 7 | 3.81 | .296 | 1.24 | 9.1 | 2.1 | 6.9 | 179.1 | 181 | 82 | 76 | 21 | 41 | 138 | 1 | 0 | 0 | 1 | 20 | 4 | 3 | 3.74 |
| CL | O'Day, D.O'Day, Darren † $$ | Orioles | R | 96.5 | 54 | 0 | 4 | 4 | 2.32 | .247 | 0.95 | 5.1 | 3.5 | 7.3 | 62.0 | 35 | 19 | 16 | 2 | 24 | 50 | 0 | 27 | 5 | 0 | 0 | 2 | 0 | 3.06 |
| SP | Burres, B.Burres, Brian † $$ | Tigers | L | 95.0 | 27 | 27 | 14 | 6 | 3.96 | .288 | 1.21 | 8.9 | 2.0 | 7.5 | 188.2 | 186 | 85 | 83 | 26 | 42 | 157 | 2 | 0 | 0 | 1 | 18 | 1 | 6 | 3.81 |
| SP | Stults, E.Stults, Eric # $$ | Tigers | L | 90.0 | 28 | 28 | 14 | 10 | 4.06 | .267 | 1.08 | 7.9 | 1.9 | 7.4 | 204.0 | 179 | 95 | 92 | 25 | 42 | 167 | 6 | 0 | 0 | 0 | 15 | 2 | 2 | 3.60 |
| CL | Marmol, C.Marmol, Carlos † $$ | Blue Jays | R | 89.5 | 56 | 0 | 5 | 6 | 3.96 | .338 | 1.52 | 7.7 | 6.0 | 7.4 | 61.1 | 52 | 27 | 27 | 8 | 41 | 50 | 0 | 27 | 1 | 0 | 0 | 1 | 2 | 5.13 |
| SP | Medlen, K.Medlen, Kris # $$ | Yankees | R | 89.0 | 29 | 29 | 15 | 8 | 4.05 | .308 | 1.31 | 8.9 | 3.0 | 7.5 | 166.2 | 164 | 90 | 75 | 28 | 55 | 138 | 1 | 0 | 0 | 1 | 17 | 4 | 0 | 4.60 |