Playoff Series Breakdown
| First Round Playoff: A's @ Astros | ||
| 1 | Astros 12, A's 6 | WP: Thompson LP: Faria |
| 2 | Astros 5, A's 4 | WP: McCullers LP: Pepiot |
| Astros Win Series 2-0 | ||
| First Round Playoff: Angels @ Guardians | ||
| 1 | Guardians 13, Angels 4 | WP: Civale LP: Gonsolin |
| 2 | Guardians 8, Angels 3 | WP: Bieber LP: Fulenchek |
| Guardians Win Series 2-0 | ||
| First Round Playoff: Mets @ Padres | ||
| 1 | Mets 4, Padres 3 | WP: Rainey LP: Castillo |
| 2 | Mets 5, Padres 4 | WP: Mayers LP: Rodriguez |
| Mets Win Series 2-0 | ||
| First Round Playoff: Rockies @ Cardinals | ||
| 1 | Rockies 11, Cardinals 0 | WP: Gray LP: Reyes |
| 2 | Cardinals 5, Rockies 2 | WP: Mahle LP: Cole |
| 3 | Cardinals 9, Rockies 1 | WP: Wacha LP: Valdez |
| Cardinals Win Series 2-1 | ||
| Second Round Playoff: Guardians @ Yankees | ||
| 1 | Guardians 12, Yankees 3 | WP: Romero LP: Severino |
| 2 | Yankees 7, Guardians 6 | WP: Tiedemann LP: Hentges |
| 3 | Yankees 4, Guardians 2 | WP: Van Hoose LP: Bieber |
| 4 | Yankees 7, Guardians 6 | WP: Hutchison LP: Vander Tuig |
| Yankees Win Series 3-1 | ||
| Second Round Playoff: Cardinals @ Dodgers | ||
| 1 | Dodgers 11, Cardinals 4 | WP: Buehler LP: Floethe |
| 2 | Cardinals 2, Dodgers 0 | WP: Siegrist LP: Phillips |
| 3 | Cardinals 6, Dodgers 4 | WP: Wacha LP: Hernandez |
| 4 | Cardinals 5, Dodgers 4 | WP: Mahle LP: Urias |
| Cardinals Win Series 3-1 | ||
| Second Round Playoff: Astros @ Rangers | ||
| 1 | Rangers 10, Astros 5 | WP: Gonzalez LP: Kime |
| 2 | Rangers 4, Astros 3 | WP: May LP: Thompson |
| 3 | Rangers 4, Astros 3 | WP: Moore LP: McCullers |
| Rangers Win Series 3-0 | ||
| Second Round Playoff: Mets @ Nationals | ||
| 1 | Nationals 4, Mets 2 | WP: Ross LP: Gsellman |
| 2 | Mets 3, Nationals 2 | WP: Rainey LP: Vega |
| 3 | Nationals 9, Mets 0 | WP: Strasburg LP: Peterson |
| 4 | Nationals 10, Mets 6 | WP: Pannone LP: Flaherty |
| Nationals Win Series 3-1 | ||
| Third Round Playoff: Yankees @ Rangers | ||
| 1 | Yankees 7, Rangers 4 | WP: Van Hoose LP: Gonzalez |
| 2 | Yankees 5, Rangers 1 | WP: Cingrani LP: May |
| 3 | Yankees 4, Rangers 1 | WP: Van Hoose LP: Moore |
| 4 | Rangers 5, Yankees 2 | WP: Fried LP: Hutchison |
| 5 | Rangers 7, Yankees 3 | WP: Gonzalez LP: Severino |
| 6 | Yankees 3, Rangers 1 | WP: Cingrani LP: May |
| Yankees Win Series 4-2 | ||
| Third Round Playoff: Cardinals @ Nationals | ||
| 1 | Cardinals 3, Nationals 2 | WP: Reyes LP: Rivero |
| 2 | Nationals 10, Cardinals 7 | WP: Burnes LP: Floethe |
| 3 | Cardinals 6, Nationals 4 | WP: Wacha LP: Strasburg |
| 4 | Cardinals 7, Nationals 6 | WP: Royalty LP: Pannone |
| 5 | Nationals 5, Cardinals 4 | WP: Pulford-Thorpe LP: Siegrist |
| 6 | Cardinals 4, Nationals 2 | WP: Floethe LP: Burnes |
| Cardinals Win Series 4-2 | ||
| World Series: Cardinals @ Yankees | ||
| 1 | Cardinals 5, Yankees 3 | WP: Jansen LP: Tiedemann |
| 2 | Yankees 4, Cardinals 0 | WP: Severino LP: Gilbreath |
| 3 | Yankees 2, Cardinals 0 | WP: Cingrani LP: Mahle |
| 4 | Yankees 3, Cardinals 1 | WP: Hutchison LP: Floethe |
| 5 | Cardinals 8, Yankees 5 | WP: Wacha LP: Urquidy |
| 6 | Yankees 5, Cardinals 1 | WP: Severino LP: Reyes |
| Yankees Win Series 4-2 | ||
