| SP | McCullers, L.McCullers, Lance † $$ | Astros | R | 173.0 | 38 | 38 | 23 | 10 | 3.76 | .274 | 1.10 | 8.2 | 1.8 | 8.6 | 313.2 | 285 | 140 | 131 | 57 | 61 | 298 | 11 | 0 | 0 | 1 | 24 | 9 | 6 | 4.13 |
| SP | Gonzalez, C.Gonzalez, Chi Chi † $ | Rangers | R | 157.0 | 39 | 39 | 20 | 9 | 3.02 | .253 | 1.01 | 6.8 | 2.3 | 6.3 | 262.1 | 197 | 92 | 88 | 36 | 68 | 184 | 2 | 0 | 0 | 1 | 29 | 2 | 3 | 4.18 |
| CL | Leclerc, J.Leclerc, Jose † $$ | Rangers | R | 155.0 | 60 | 0 | 3 | 2 | 1.73 | .232 | 0.91 | 4.1 | 4.1 | 10.1 | 57.1 | 26 | 11 | 11 | 4 | 26 | 64 | 0 | 48 | 1 | 0 | 0 | 0 | 1 | 3.04 |
| SP | Civale, A.Civale, Aaron + $$ | Guardians | R | 154.0 | 36 | 36 | 23 | 7 | 3.92 | .294 | 1.23 | 7.8 | 3.2 | 7.4 | 250.0 | 217 | 113 | 109 | 31 | 90 | 206 | 5 | 0 | 0 | 2 | 24 | 6 | 5 | 4.12 |
| SP | Faria, J.Faria, Jake # $$ | A's | R | 146.0 | 37 | 37 | 21 | 9 | 3.66 | .257 | 1.02 | 7.4 | 1.8 | 9.6 | 243.1 | 200 | 103 | 99 | 37 | 49 | 259 | 2 | 0 | 0 | 0 | 23 | 3 | 8 | 3.49 |
| SP | Ohtani, S.Ohtani, Shohei † $$ | Royals | R | 143.0 | 36 | 36 | 17 | 11 | 2.99 | .270 | 1.09 | 6.3 | 3.5 | 10.5 | 247.0 | 173 | 84 | 82 | 28 | 95 | 289 | 1 | 0 | 0 | 0 | 26 | 6 | 6 | 3.36 |
| RP | Van Hoose, C.Van Hoose, Connor † $$ | Yankees | R | 143.0 | 90 | 0 | 16 | 4 | 3.33 | .264 | 1.06 | 6.7 | 2.9 | 8.6 | 203.0 | 150 | 81 | 75 | 18 | 65 | 195 | 0 | 8 | 2 | 0 | 0 | 3 | 8 | 3.24 |
| CL | Mesa Jr., J.Mesa Jr., Jose † $$ | Red Sox | L | 135.0 | 62 | 0 | 4 | 8 | 2.50 | .240 | 0.92 | 5.4 | 2.9 | 6.5 | 119.0 | 71 | 34 | 33 | 13 | 39 | 86 | 0 | 38 | 4 | 0 | 0 | 3 | 2 | 4.03 |
| CL | Misiaszek, A.Misiaszek, Andrew $$ | Orioles | L | 121.5 | 44 | 0 | 3 | 1 | 2.45 | .250 | 1.00 | 5.7 | 3.3 | 9.4 | 44.0 | 28 | 12 | 12 | 4 | 16 | 46 | 0 | 39 | 4 | 0 | 0 | 0 | 1 | 3.18 |