Playoff Series Breakdown
| Play-In Round: Giants @ Astros | ||
| 1 | Astros 2, Giants 1 | WP: Osuna LP: Strickland |
| 2 | Astros 16, Giants 8 | WP: Anderson LP: Tomlin |
| 3 | Giants 7, Astros 4 | WP: Bumgarner LP: McHugh |
| 4 | Astros 2, Giants 1 | WP: Sipp LP: Moronta |
| Astros Win Series 3-1 | ||
| Play-In Round: A's @ Indians | ||
| 1 | Indians 2, A's 1 | WP: Kluber LP: Fiers |
| 2 | Indians 4, A's 2 | WP: Hand LP: Archer |
| 3 | A's 2, Indians 1 | WP: Manaea LP: Carrasco |
| 4 | Indians 7, A's 5 | WP: Cervenka LP: Cook |
| Indians Win Series 3-1 | ||
| Play-In Round: White Sox @ Yankees | ||
| 1 | Yankees 7, White Sox 0 | WP: Tanaka LP: Giolito |
| 2 | Yankees 7, White Sox 6 | WP: Chapman LP: Manship |
| 3 | White Sox 3, Yankees 1 | WP: Stewart LP: Lamet |
| 4 | Yankees 3, White Sox 0 | WP: Tanaka LP: Giolito |
| Yankees Win Series 3-1 | ||
| Play-In Round: Cubs @ Braves | ||
| 1 | Braves 3, Cubs 2 | WP: Hernandez LP: Edwards |
| 2 | Cubs 1, Braves 0 | WP: Strasburg LP: Foltynewicz |
| 3 | Braves 3, Cubs 1 | WP: Teheran LP: Darvish |
| 4 | Braves 5, Cubs 2 | WP: Leone LP: Familia |
| Braves Win Series 3-1 | ||
| Second Round Playoff: Indians @ Yankees | ||
| 1 | Yankees 3, Indians 0 | WP: Tanaka LP: Kluber |
| 2 | Yankees 5, Indians 4 | WP: Severino LP: Bauer |
| 3 | Indians 5, Yankees 3 | WP: Carrasco LP: Lamet |
| 4 | Indians 6, Yankees 5 | WP: Gray LP: Montgomery |
| 5 | Yankees 1, Indians 0 | WP: Tanaka LP: Kluber |
| Yankees Win Series 3-2 | ||
| Second Round Playoff: Astros @ Braves | ||
| 1 | Braves 8, Astros 0 | WP: Hernandez LP: Verlander |
| 2 | Braves 6, Astros 1 | WP: Foltynewicz LP: Keuchel |
| 3 | Braves 10, Astros 2 | WP: Teheran LP: McHugh |
| Braves Win Series 3-0 | ||
| Third Round Playoff: Braves @ Dodgers | ||
| 1 | Dodgers 3, Braves 1 | WP: Kershaw LP: Hernandez |
| 2 | Dodgers 2, Braves 0 | WP: Buehler LP: Foltynewicz |
| 3 | Braves 8, Dodgers 6 | WP: Teheran LP: Greinke |
| 4 | Braves 4, Dodgers 3 | WP: Toussaint LP: Hill |
| 5 | Braves 4, Dodgers 1 | WP: Hernandez LP: Kershaw |
| 6 | Dodgers 8, Braves 1 | WP: Buehler LP: Foltynewicz |
| 7 | Dodgers 5, Braves 4 | WP: Garcia LP: Neris |
| Dodgers Win Series 4-3 | ||
| Third Round Playoff: Yankees @ Red Sox | ||
| 1 | Red Sox 5, Yankees 0 | WP: Sale LP: Tanaka |
| 2 | Red Sox 11, Yankees 0 | WP: Cueto LP: Severino |
| 3 | Red Sox 2, Yankees 1 | WP: Pomeranz LP: Lamet |
| 4 | Yankees 5, Red Sox 4 | WP: Cessa LP: Romo |
| 5 | Yankees 1, Red Sox 0 | WP: Tanaka LP: Sale |
| 6 | Red Sox 5, Yankees 1 | WP: Cueto LP: Severino |
| Red Sox Win Series 4-2 | ||
| World Series: Red Sox @ Dodgers | ||
| 1 | Red Sox 4, Dodgers 2 | WP: Sale LP: Kershaw |
| 2 | Red Sox 10, Dodgers 2 | WP: Cueto LP: Buehler |
| 3 | Dodgers 9, Red Sox 4 | WP: Greinke LP: Pomeranz |
| 4 | Dodgers 4, Red Sox 1 | WP: Hill LP: Porcello |
| 5 | Dodgers 4, Red Sox 3 | WP: Kershaw LP: Sale |
| 6 | Dodgers 3, Red Sox 2 | WP: Baez LP: Harris |
| Dodgers Win Series 4-2 | ||
