Playoff Series Breakdown
| First Round Playoff: Reds @ Phillies | ||
| 1 | Phillies 4, Reds 1 | WP: Nola LP: Adleman |
| 2 | Reds 7, Phillies 3 | WP: Castillo LP: Leiter |
| 3 | Reds 12, Phillies 5 | WP: Stephens LP: Hellickson |
| Reds Win Series 2-1 | ||
| First Round Playoff: Rays @ Angels | ||
| 1 | Angels 4, Rays 1 | WP: Bridwell LP: Snell |
| 2 | Angels 4, Rays 1 | WP: Richards LP: Faria |
| Angels Win Series 2-0 | ||
| First Round Playoff: A's @ Astros | ||
| 1 | Astros 5, A's 0 | WP: Keuchel LP: Blackburn |
| 2 | Astros 6, A's 3 | WP: Devenski LP: Gray |
| Astros Win Series 2-0 | ||
| First Round Playoff: Cubs @ Cardinals | ||
| 1 | Cardinals 5, Cubs 0 | WP: Weaver LP: Arrieta |
| 2 | Cubs 4, Cardinals 2 | WP: Davis LP: Tuivailala |
| 3 | Cubs 8, Cardinals 5 | WP: Davis LP: Wacha |
| Cubs Win Series 2-1 | ||
| Second Round Playoff: Indians @ Angels | ||
| 1 | Indians 6, Angels 2 | WP: Kluber LP: Meyer |
| 2 | Indians 2, Angels 1 | WP: Carrasco LP: Richards |
| 3 | Angels 4, Indians 3 | WP: Hernandez LP: Shaw |
| 4 | Angels 8, Indians 3 | WP: Skaggs LP: Bauer |
| 5 | Indians 5, Angels 1 | WP: Kluber LP: Meyer |
| Indians Win Series 3-2 | ||
| Second Round Playoff: Yankees @ Astros | ||
| 1 | Astros 3, Yankees 1 | WP: Keuchel LP: Severino |
| 2 | Astros 12, Yankees 5 | WP: Verlander LP: Gray |
| 3 | Astros 8, Yankees 4 | WP: Morton LP: Montgomery |
| Astros Win Series 3-0 | ||
| Second Round Playoff: Diamondbacks @ Cubs | ||
| 1 | Diamondbacks 8, Cubs 2 | WP: Ray LP: Arrieta |
| 2 | Diamondbacks 8, Cubs 4 | WP: Greinke LP: Hendricks |
| 3 | Diamondbacks 6, Cubs 5 | WP: Bradley LP: Uehara |
| Diamondbacks Win Series 3-0 | ||
| Second Round Playoff: Pirates @ Reds | ||
| 1 | Reds 5, Pirates 4 | WP: Shackelford LP: Rivero |
| 2 | Pirates 8, Reds 0 | WP: Williams LP: Feldman |
| 3 | Reds 8, Pirates 5 | WP: Lorenzen LP: Rivero |
| 4 | Pirates 4, Reds 1 | WP: Kuhl LP: Stephenson |
| 5 | Pirates 6, Reds 2 | WP: Cole LP: Castillo |
| Pirates Win Series 3-2 | ||
| Third Round Playoff: Pirates @ Diamondbacks | ||
| 1 | Pirates 1, Diamondbacks 0 | WP: Kontos LP: Ray |
| 2 | Diamondbacks 5, Pirates 1 | WP: Greinke LP: Nova |
| 3 | Diamondbacks 9, Pirates 5 | WP: Godley LP: Cole |
| 4 | Pirates 5, Diamondbacks 2 | WP: Kuhl LP: Walker |
| 5 | Diamondbacks 7, Pirates 5 | WP: Delgado LP: Rivero |
| 6 | Diamondbacks 5, Pirates 0 | WP: Greinke LP: Taillon |
| 7 | Diamondbacks 2, Pirates 0 | WP: Godley LP: Cole |
| Diamondbacks Win Series 5-2 | ||
| Third Round Playoff: Astros @ Indians | ||
| 1 | Astros 5, Indians 4 | WP: Keuchel LP: Kluber |
| 2 | Indians 5, Astros 2 | WP: Carrasco LP: Verlander |
| 3 | Astros 3, Indians 2 | WP: Devenski LP: Allen |
| 4 | Astros 9, Indians 4 | WP: Clippard LP: Bauer |
| 5 | Astros 14, Indians 3 | WP: Keuchel LP: Kluber |
| Astros Win Series 4-1 | ||
| World Series: Astros @ Diamondbacks | ||
| 1 | Diamondbacks 8, Astros 1 | WP: Ray LP: Keuchel |
| 2 | Diamondbacks 5, Astros 3 | WP: Greinke LP: Verlander |
| 3 | Astros 4, Diamondbacks 2 | WP: Clippard LP: Delgado |
| 4 | Astros 3, Diamondbacks 0 | WP: McCullers LP: Walker |
| 5 | Astros 6, Diamondbacks 1 | WP: Keuchel LP: Ray |
| 6 | Diamondbacks 5, Astros 0 | WP: Greinke LP: Verlander |
| 7 | Diamondbacks 3, Astros 0 | WP: Godley LP: Morton |
| Diamondbacks Win Series 4-3 | ||
