| SP | Eovaldi, N.Eovaldi, Nathan | 28 | Rays | R | 68.0 | 13 | 13 | 8 | 1 | 1.90 | .272 | 1.08 | 7.7 | 2.2 | 7.7 | 75.2 | 64 | 17 | 16 | 2 | 18 | 64 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 2.48 |
| SP | Kluber, C.Kluber, Corey # | 32 | Indians | R | 56.0 | 13 | 13 | 7 | 1 | 3.67 | .284 | 1.13 | 7.9 | 2.3 | 11.3 | 90.2 | 79 | 37 | 37 | 12 | 23 | 113 | 1 | 0 | 0 | 0 | 9 | 6 | 2 | 3.19 |
| SP | Montgomery, J.Montgomery, Jordan | 25 | Yankees | L | 52.0 | 13 | 13 | 7 | 3 | 3.07 | .274 | 1.10 | 7.5 | 2.4 | 8.2 | 82.0 | 68 | 28 | 28 | 9 | 22 | 75 | 0 | 0 | 0 | 0 | 9 | 3 | 2 | 3.51 |
| SP | Johnson, B.Johnson, Brian | 27 | Red Sox | L | 45.0 | 12 | 12 | 5 | 2 | 2.84 | .292 | 1.21 | 8.3 | 2.6 | 8.5 | 76.0 | 70 | 27 | 24 | 5 | 22 | 72 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 2.91 |
| SP | Sanchez, A.Sanchez, Anibal | 34 | Tigers | R | 44.0 | 13 | 13 | 5 | 3 | 2.66 | .288 | 1.16 | 6.8 | 3.6 | 10.1 | 74.1 | 56 | 29 | 22 | 7 | 30 | 83 | 0 | 0 | 0 | 0 | 8 | 4 | 0 | 3.36 |
| SP | Mengden, D.Mengden, Daniel # | 25 | A's | R | 42.0 | 13 | 13 | 5 | 2 | 3.27 | .305 | 1.29 | 9.4 | 2.3 | 8.7 | 82.2 | 86 | 31 | 30 | 12 | 21 | 79 | 0 | 0 | 0 | 0 | 9 | 2 | 2 | 3.82 |
| SP | McCullers, L.McCullers, Lance | 25 | Astros | R | 40.0 | 19 | 0 | 7 | 0 | 4.88 | .327 | 1.36 | 9.0 | 3.2 | 9.2 | 59.0 | 59 | 32 | 32 | 10 | 21 | 60 | 0 | 0 | 0 | 0 | 0 | 6 | 7 | 4.54 |
| SP | Verlander, J.Verlander, Justin | 35 | Astros | R | 38.0 | 13 | 13 | 6 | 4 | 3.84 | .321 | 1.39 | 9.5 | 3.2 | 10.7 | 79.2 | 83 | 35 | 34 | 16 | 28 | 94 | 0 | 0 | 0 | 0 | 8 | 2 | 2 | 4.39 |