Playoff Series Breakdown
| First Round Playoff: Twins @ White Sox | ||
| 1 | Twins 5, White Sox 2 | WP: Yamamoto LP: Cole |
| 2 | White Sox 14, Twins 4 | WP: Fried LP: Glasnow |
| 3 | White Sox 3, Twins 2 | WP: Rodon LP: Sheehan |
| 4 | White Sox 17, Twins 15 | WP: Cortes Jr. LP: Ober |
| White Sox Win Series 3-1 | ||
| First Round Playoff: Braves @ Red Sox | ||
| 1 | Red Sox 2, Braves 0 | WP: Wheeler LP: Rogers |
| 2 | Red Sox 7, Braves 5 | WP: Hoffman LP: Akin |
| 3 | Red Sox 4, Braves 3 | WP: Strahm LP: Iglesias |
| Red Sox Win Series 3-0 | ||
| Second Round Playoff: White Sox @ Red Sox | ||
| 1 | White Sox 7, Red Sox 1 | WP: Fried LP: Wheeler |
| 2 | Red Sox 6, White Sox 2 | WP: Turnbull LP: Bednar |
| 3 | Red Sox 5, White Sox 2 | WP: Sanchez LP: Cole |
| 4 | Red Sox 9, White Sox 6 | WP: Strahm LP: Gil |
| 5 | White Sox 3, Red Sox 2 | WP: Williams LP: Chapman |
| 6 | White Sox 2, Red Sox 0 | WP: Rodon LP: Crochet |
| 7 | Red Sox 7, White Sox 1 | WP: Sanchez LP: Cole |
| Red Sox Win Series 4-3 | ||
| World Series: Red Sox @ Cubs | ||
| 1 | Cubs 1, Red Sox 0 | WP: Skubal LP: Wheeler |
| 2 | Cubs 4, Red Sox 3 | WP: Hodge LP: Chapman |
| 3 | Cubs @ Red Sox | |
| 4 | Cubs @ Red Sox | |
| 5 | Cubs @ Red Sox | |
| 6 | Red Sox @ Cubs | |
| 7 | Red Sox @ Cubs | |
| Cubs Lead Series 2-0 | ||
