| C(1B) | Vazquez, C.Vazquez, Christian >> | 25 | 2016 | R | 25 | 17 | 84 | 57 | .227 | .281 | .308 | .589 | .250 | 172 | 21 | 39 | 9 | 1 | 1 | 12 | 10 | 39 | 3 | 0 | .996 | - | +0.24 | 2 | -0.23 | 5 | C |
| 1B(DH) | Ramirez, H.Ramirez, Hanley >> | 33 | 2016 | R | 89 | 94 | 25 | 147 | .286 | .374 | .505 | .879 | .350 | 549 | 81 | 157 | 28 | 1 | 30 | 111 | 60 | 120 | 17 | 9 | .996 | - | -1.38 | 3 | +3.23 | 13 | C |
| 2B(IF) | Pedroia, D.Pedroia, Dustin † >> | 33 | 2016 | R | 100 | 98 | 96 | 154 | .318 | .398 | .449 | .847 | .370 | 633 | 105 | 201 | 36 | 1 | 15 | 74 | 61 | 73 | 24 | 7 | .990 | - | +1.69 | 3 | +4.35 | 22 | C |
| 3B(1B) | Shaw, T.Shaw, Travis # >> | 26 | 2016 | L | 58 | 47 | 78 | 145 | .242 | .317 | .421 | .738 | .290 | 480 | 63 | 116 | 34 | 2 | 16 | 71 | 43 | 133 | 10 | 5 | .971 | - | +1.39 | 3 | +0.75 | 12 | C |
| SS(IF) | Iglesias, J.Iglesias, Jose # >> | 26 | 2016 | R | 52 | 38 | 94 | 137 | .255 | .308 | .336 | .644 | .280 | 467 | 57 | 119 | 26 | 0 | 4 | 32 | 28 | 50 | 8 | 7 | .991 | - | +1.05 | 3 | +1.49 | 8 | C |
| SS(UT) | Gregorius, D.Gregorius, Didi >> | 26 | 2016 | L | 49 | 61 | 32 | 153 | .276 | .307 | .447 | .754 | .280 | 562 | 68 | 155 | 32 | 2 | 20 | 70 | 19 | 82 | 6 | 7 | .974 | - | -0.09 | 3 | +3.1 | 20 | C |
| OF(OF) | Benintendi, A.Benintendi, Andrew # >> | 22 | 2016 | L | 83 | 90 | 33 | 34 | .295 | .357 | .476 | .833 | .330 | 105 | 16 | 31 | 11 | 1 | 2 | 14 | 10 | 25 | 0 | 1 | .982 | - | -0.21 | 4 | +0.63 | 4 | C |
| OF(OF) | Betts, M.Betts, Mookie † >> | 23 | 2016 | R | 100 | 99 | 100 | 158 | .318 | .375 | .534 | .909 | .350 | 672 | 122 | 214 | 42 | 5 | 31 | 113 | 49 | 80 | 12 | 26 | .997 | - | +2.78 | 6 | +6.14 | 42 | C |
| OF(OF) | Reddick, J.Reddick, Josh # >> | 29 | 2016 | L | 76 | 75 | 51 | 115 | .281 | .346 | .405 | .751 | .320 | 398 | 53 | 112 | 17 | 1 | 10 | 37 | 39 | 56 | 0 | 8 | .973 | - | +0.18 | 4 | +1.99 | 5 | C |
| OF(OF) | Bradley, J.Bradley, Jackie >> | 26 | 2016 | L | 91 | 81 | 98 | 156 | .267 | .352 | .486 | .838 | .320 | 558 | 94 | 149 | 30 | 7 | 26 | 87 | 63 | 143 | 10 | 9 | .992 | - | +1.56 | 5 | +4.13 | 29 | C |
| OF(C) | Swihart, B.Swihart, Blake >> | 24 | 2016 | S | 82 | 68 | 74 | 19 | .258 | .370 | .355 | .725 | .340 | 62 | 9 | 16 | 0 | 3 | 0 | 5 | 11 | 17 | 0 | 0 | 1.000 | - | -0.01 | 8 | +0.23 | 4 | C |