| SP | Martinez, P.Martinez, Pedro # >> | 30 | 2000 | R | 100 | 18 | 6 | 1.74 | .195 | .270 | 0.74 | 5.3 | 1.3 | 11.8 | 217 | 128 | 17 | 32 | 284 | 7 | 0 | 1 | 131 | 21 | C |
| SP | deGrom, J.deGrom, Jacob >> | 34 | 2022 | R | 100 | 5 | 4 | 3.08 | .192 | .270 | 0.75 | 5.6 | 1.1 | 14.3 | 64 | 40 | 9 | 8 | 102 | 0 | 0 | 0 | 103 | 24 | C |
| SP | Scherzer, M.Scherzer, Max >> | 38 | 2022 | R | 92 | 11 | 5 | 2.29 | .229 | .300 | 0.91 | 6.7 | 1.5 | 10.7 | 145 | 108 | 13 | 24 | 173 | 0 | 0 | 1 | 111 | 20 | C |
| SP | Sale, C.Sale, Chris # >> | 31 | 2019 | L | 81 | 6 | 11 | 4.40 | .262 | .330 | 1.09 | 7.5 | 2.3 | 13.3 | 147 | 123 | 24 | 37 | 218 | 1 | 0 | 2 | 104 | 23 | C |
| SP | Beckett, J.Beckett, Josh # >> | 28 | 2007 | R | 67 | 20 | 7 | 3.27 | .269 | .340 | 1.12 | 8.4 | 1.7 | 8.8 | 203 | 189 | 17 | 39 | 199 | 1 | 0 | 3 | 122 | 19 | C |
| CL | Kimbrel, C.Kimbrel, Craig >> | 30 | 2017 | R | 100 | 5 | 0 | 1.43 | .178 | .250 | 0.68 | 4.3 | 1.8 | 16.4 | 69 | 33 | 6 | 14 | 126 | 0 | 35 | 5 | 23 | 28 | C |
| SU | Papelbon, J.Papelbon, Jonathan >> | 28 | 2007 | R | 99 | 1 | 3 | 1.85 | .187 | .260 | 0.73 | 4.4 | 2.2 | 12.9 | 62 | 30 | 5 | 15 | 89 | 0 | 37 | 0 | 25 | 25 | C |
| RP | Diaz, E.Diaz, Edwin >> | 28 | 2022 | R | 98 | 3 | 1 | 1.31 | .210 | .290 | 0.84 | 4.9 | 2.6 | 17.1 | 62 | 34 | 3 | 18 | 118 | 0 | 32 | 2 | 23 | 29 | C |
| RP | Workman, B.Workman, Brandon >> | 31 | 2019 | R | 91 | 10 | 1 | 1.88 | .249 | .330 | 1.04 | 3.7 | 5.7 | 13.2 | 71 | 29 | 1 | 45 | 104 | 0 | 16 | 4 | 23 | 24 | C |
| RP | Delcarmen, M.Delcarmen, Manny >> | 26 | 2007 | R | 90 | 0 | 0 | 2.05 | .230 | .310 | 0.96 | 5.4 | 3.3 | 8.4 | 47 | 28 | 4 | 17 | 44 | 0 | 1 | 0 | 25 | 21 | C |
| RP | Ottavino, A.Ottavino, Adam >> | 36 | 2022 | R | 87 | 6 | 3 | 2.06 | .238 | .320 | 0.98 | 6.6 | 2.2 | 10.9 | 65 | 48 | 6 | 16 | 79 | 0 | 3 | 7 | 23 | 21 | C |
| RP | Okajima, H.Okajima, Hideki >> | 33 | 2007 | L | 77 | 3 | 2 | 2.22 | .252 | .330 | 1.06 | 6.8 | 2.7 | 7.4 | 69 | 52 | 6 | 21 | 57 | 0 | 5 | 0 | 20 | 18 | C |
| RP | Taylor, J.Taylor, Josh >> | 27 | 2019 | L | 72 | 2 | 2 | 3.04 | .263 | .340 | 1.14 | 7.3 | 2.9 | 12.3 | 49 | 40 | 5 | 16 | 67 | 0 | 0 | 3 | 25 | 23 | C |
| RP | Smith, D.Smith, Drew >> | 28 | 2022 | R | 70 | 3 | 3 | 3.33 | .264 | .350 | 1.15 | 7.4 | 2.9 | 10.4 | 46 | 38 | 9 | 15 | 53 | 0 | 0 | 0 | 23 | 20 | C |
| RP | Lugo, S.Lugo, Seth >> | 32 | 2022 | R | 63 | 3 | 2 | 3.60 | .270 | .350 | 1.17 | 8.0 | 2.5 | 9.6 | 65 | 58 | 9 | 18 | 69 | 0 | 3 | 2 | 23 | 19 | C |
| SP | Rodriguez, E.Rodriguez, Eduardo >> | 27 | 2019 | L | 52 | 19 | 6 | 3.81 | .296 | .370 | 1.28 | 8.5 | 3.0 | 9.6 | 206 | 195 | 24 | 69 | 220 | 0 | 0 | 3 | 107 | 20 | C |
| SP | Gabbard, K.Gabbard, Kason >> | 26 | 2007 | L | 67 | 6 | 1 | 4.65 | .278 | .350 | 1.20 | 7.1 | 3.7 | 6.4 | 86 | 68 | 8 | 35 | 61 | 1 | 0 | 5 | 101 | 17 | C |
| SP | Walker, T.Walker, Taijuan >> | 29 | 2022 | R | 60 | 12 | 5 | 3.49 | .281 | .350 | 1.20 | 8.2 | 2.6 | 7.6 | 157 | 143 | 15 | 45 | 132 | 0 | 0 | 0 | 96 | 17 | C |
| RP | Hembree, H.Hembree, Heath >> | 31 | 2019 | R | 48 | 1 | 0 | 3.86 | .291 | .380 | 1.33 | 7.8 | 4.2 | 10.6 | 39 | 34 | 7 | 18 | 46 | 0 | 2 | 2 | 23 | 21 | C |
| SP | Bassitt, C.Bassitt, Chris >> | 33 | 2022 | R | 69 | 15 | 9 | 3.42 | .273 | .350 | 1.15 | 7.9 | 2.4 | 8.3 | 181 | 159 | 19 | 49 | 167 | 0 | 0 | 5 | 107 | 18 | C |
| SP | Matsuzaka, D.Matsuzaka, Daisuke >> | 28 | 2007 | R | 50 | 15 | 12 | 4.40 | .300 | .370 | 1.31 | 8.3 | 3.4 | 8.9 | 206 | 191 | 25 | 78 | 204 | 1 | 0 | 5 | 116 | 20 | C |
| RP | Rodriguez, J.Rodriguez, Joely >> | 30 | 2022 | L | 47 | 2 | 4 | 4.47 | .298 | .380 | 1.36 | 7.6 | 4.7 | 10.3 | 50 | 42 | 3 | 26 | 57 | 0 | 0 | 2 | 23 | 21 | C |
| RP | Walden, M.Walden, Marcus >> | 31 | 2019 | R | 67 | 9 | 2 | 3.81 | .276 | .350 | 1.19 | 7.0 | 3.7 | 8.8 | 78 | 61 | 6 | 32 | 76 | 0 | 2 | 6 | 23 | 19 | C |
| RP | Barnes, M.Barnes, Matt >> | 30 | 2019 | R | 51 | 5 | 4 | 3.78 | .306 | .390 | 1.39 | 7.2 | 5.3 | 15.5 | 64 | 51 | 8 | 38 | 110 | 0 | 4 | 13 | 23 | 25 | C |
| RP | Megill, T.Megill, Tylor >> | 26 | 2022 | R | 48 | 4 | 2 | 5.13 | .281 | .360 | 1.26 | 8.8 | 2.5 | 9.8 | 47 | 46 | 7 | 13 | 51 | 0 | 0 | 1 | 57 | 20 | C |
| SP | Peterson, D.Peterson, David >> | 26 | 2022 | L | 51 | 7 | 5 | 3.83 | .303 | .380 | 1.34 | 8.0 | 4.1 | 10.8 | 105 | 93 | 11 | 48 | 126 | 0 | 0 | 3 | 68 | 21 | C |