| SP | Scherzer, M.Scherzer, Max >> | 29 | 2013 | R | 70 | 21 | 3 | 2.90 | .242 | .330 | 0.97 | 6.4 | 2.4 | 10.1 | 214 | 152 | 18 | 56 | 240 | 0 | 0 | 6 | 118 | +6.41 | C |
| RP | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 52 | 3 | 1 | 2.02 | .218 | .320 | 0.91 | 5.7 | 2.6 | 8.5 | 35 | 22 | 2 | 10 | 33 | 0 | 1 | 3 | 34 | +0.83 | C |
| RP | Greene, S.Greene, Shane >> | 30 | 2019 | R | 70 | 0 | 2 | 1.18 | .210 | .310 | 0.87 | 5.0 | 2.8 | 10.2 | 38 | 21 | 5 | 12 | 43 | 0 | 22 | 0 | 23 | +1.72 | C |
| RP | Rondon, B.Rondon, Bruce >> | 25 | 2016 | R | 41 | 5 | 2 | 2.97 | .229 | .330 | 0.97 | 5.8 | 3.0 | 11.3 | 36 | 23 | 5 | 12 | 45 | 0 | 0 | 1 | 23 | +1.01 | C |
| RP | Hurter, B.Hurter, Brant >> | 25 | 2024 | L | 40 | 6 | 1 | 2.58 | .216 | .310 | 0.89 | 6.8 | 1.2 | 7.6 | 45 | 34 | 4 | 6 | 38 | 0 | 0 | 0 | 40 | +1.3 | C |
| SP | Lolich, M.Lolich, Mickey >> | 28 | 1968 | L | 18 | 17 | 9 | 3.19 | .266 | .350 | 1.10 | 7.3 | 2.7 | 8.1 | 220 | 178 | 23 | 65 | 197 | 8 | 1 | 3 | 100 | +0.91 | C |
| SP | Verlander, J.Verlander, Justin >> | 28 | 2011 | R | 84 | 24 | 5 | 2.40 | .232 | .320 | 0.92 | 6.2 | 2.0 | 9.0 | 251 | 174 | 24 | 57 | 250 | 4 | 0 | 7 | 130 | +8.61 | C |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 77 | 31 | 6 | 1.96 | .230 | .310 | 0.90 | 6.5 | 1.7 | 7.5 | 336 | 241 | 31 | 63 | 280 | 28 | 0 | 3 | 140 | +7.42 | C |
| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 87 | 13 | 6 | 2.21 | .226 | .310 | 0.89 | 6.5 | 1.5 | 11.1 | 195 | 141 | 18 | 33 | 241 | 1 | 0 | 3 | 111 | +6.6 | C |
| RP | Wilson, J.Wilson, Justin >> | 29 | 2017 | L | 60 | 3 | 4 | 2.68 | .226 | .320 | 0.95 | 5.0 | 3.6 | 12.4 | 40 | 22 | 5 | 16 | 55 | 0 | 13 | 3 | 23 | +1.56 | C |
| RP | Alburquerque, A.Alburquerque, Al >> | 25 | 2011 | R | 45 | 6 | 1 | 1.87 | .265 | .360 | 1.16 | 4.4 | 6.1 | 14.0 | 43 | 21 | 0 | 29 | 67 | 0 | 0 | 4 | 23 | +1.53 | C |
| RP | Melton, T.Melton, Troy >> | 24 | 2025 | R | 18 | 3 | 2 | 2.76 | .241 | .340 | 1.02 | 6.2 | 3.0 | 7.2 | 45 | 31 | 7 | 15 | 36 | 0 | 0 | 2 | 52 | +1 | C |