| SP | Johnson, W.Johnson, Walter + >> | 45 | 1913 | R | 59 | 18 | 18 | 2 | 13 | 3.93 | .292 | 1.23 | 7.7 | 3.4 | 5.8 | 121.1 | 103 | 58 | 53 | 17 | 46 | 78 | 0 | 0 | 0 | 0 | 12 | 1 | 2 | 4.70 |
| SP | Blyleven, B.Blyleven, Bert >> | 40 | 1972 | R | 52 | 18 | 18 | 2 | 15 | 6.06 | .341 | 1.54 | 10.5 | 3.5 | 5.6 | 130.2 | 151 | 99 | 88 | 22 | 50 | 81 | 5 | 0 | 0 | 0 | 7 | 2 | 5 | 5.15 |
| SP | Santana, J.Santana, Johan >> | 44 | 2005 | L | 26 | 18 | 18 | 2 | 13 | 6.11 | .342 | 1.54 | 10.2 | 3.6 | 5.0 | 109.0 | 124 | 76 | 74 | 21 | 44 | 61 | 1 | 0 | 0 | 0 | 5 | 2 | 4 | 5.65 |
| RP | Durocher, J.Durocher, Jayson >> | 43 | 2002 | R | 5 | 46 | 0 | 1 | 0 | 4.79 | .310 | 1.35 | 7.7 | 4.6 | 3.3 | 35.2 | 30 | 20 | 19 | 6 | 18 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 6.03 |
| SU | LaRoche, D.LaRoche, Dave >> | 43 | 1972 | L | 7 | 25 | 0 | 1 | 1 | 6.23 | .330 | 1.48 | 10.7 | 3.0 | 5.6 | 21.2 | 25 | 15 | 15 | 2 | 7 | 13 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 4.00 |
| RP | Villanueva, C.Villanueva, Carlos >> | 37 | 2007 | R | 22 | 37 | 0 | 2 | 1 | 6.23 | .373 | 1.76 | 11.5 | 4.6 | 6.1 | 47.2 | 60 | 34 | 33 | 6 | 24 | 32 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 4.89 |
| CL | Guardado, E.Guardado, Eddie >> | 42 | 1996 | L | 2 | 24 | 0 | 2 | 2 | 4.70 | .337 | 1.48 | 7.8 | 5.5 | 2.7 | 23.0 | 20 | 13 | 12 | 4 | 14 | 7 | 0 | 10 | 2 | 0 | 0 | 1 | 1 | 6.61 |
| SP | Gallardo, Y.Gallardo, Yovani >> | 34 | 2007 | R | 72 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Smithson, M.Smithson, Mike >> | 37 | 1984 | R | 17 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 40 | 2005 | L | 24 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Butcher, J.Butcher, John >> | 35 | 1984 | R | 14 | 9 | 0 | 0 | 3 | 3.55 | .255 | 1.03 | 8.3 | 1.5 | 6.8 | 12.2 | 11 | 5 | 5 | 3 | 2 | 9 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.25 |