| SP | Johnson, W.Johnson, Walter + >> | 45 | 1913 | R | 59 | 29 | 29 | 4 | 19 | 4.67 | .299 | 1.27 | 8.5 | 2.9 | 5.7 | 188.2 | 178 | 104 | 98 | 33 | 61 | 120 | 0 | 0 | 0 | 0 | 15 | 2 | 4 | 5.01 |
| SP | Blyleven, B.Blyleven, Bert >> | 40 | 1972 | R | 52 | 29 | 29 | 3 | 24 | 6.43 | .345 | 1.57 | 10.4 | 3.7 | 6.3 | 203.0 | 234 | 164 | 145 | 37 | 84 | 143 | 7 | 0 | 0 | 0 | 9 | 3 | 7 | 5.25 |
| SP | Santana, J.Santana, Johan >> | 44 | 2005 | L | 26 | 29 | 29 | 4 | 21 | 5.52 | .338 | 1.51 | 10.2 | 3.3 | 5.2 | 181.0 | 206 | 119 | 111 | 33 | 67 | 105 | 2 | 0 | 0 | 1 | 10 | 4 | 4 | 5.39 |
| RP | Durocher, J.Durocher, Jayson >> | 43 | 2002 | R | 5 | 75 | 0 | 1 | 0 | 4.50 | .315 | 1.38 | 8.2 | 4.2 | 3.1 | 58.0 | 53 | 33 | 29 | 8 | 27 | 20 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.50 |
| SU | LaRoche, D.LaRoche, Dave >> | 43 | 1972 | L | 7 | 46 | 0 | 3 | 1 | 5.79 | .340 | 1.55 | 9.9 | 4.1 | 5.4 | 42.0 | 46 | 27 | 27 | 6 | 19 | 25 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 5.02 |
| RP | Villanueva, C.Villanueva, Carlos >> | 37 | 2007 | R | 22 | 60 | 0 | 2 | 1 | 5.74 | .363 | 1.69 | 11.3 | 3.9 | 6.2 | 78.1 | 98 | 51 | 50 | 8 | 34 | 54 | 0 | 1 | 2 | 0 | 0 | 2 | 2 | 4.33 |
| CL | Guardado, E.Guardado, Eddie >> | 42 | 1996 | L | 2 | 41 | 0 | 3 | 4 | 6.56 | .378 | 1.79 | 9.8 | 6.7 | 4.4 | 35.2 | 38 | 29 | 26 | 5 | 26 | 17 | 0 | 13 | 4 | 0 | 0 | 1 | 1 | 6.20 |
| SP | Gallardo, Y.Gallardo, Yovani >> | 34 | 2007 | R | 72 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Smithson, M.Smithson, Mike >> | 37 | 1984 | R | 17 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 40 | 2005 | L | 24 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Butcher, J.Butcher, John >> | 35 | 1984 | R | 14 | 13 | 0 | 0 | 4 | 6.11 | .321 | 1.42 | 10.6 | 2.6 | 6.4 | 17.2 | 20 | 12 | 12 | 6 | 5 | 12 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 7.06 |