| SP | Villa, P.Villa, Poncho $$ >> | 28 | 1898 | R | 99 | 35 | 35 | 11 | 10 | 3.52 | .279 | 1.11 | 6.3 | 3.7 | 7.4 | 212.1 | 149 | 99 | 83 | 24 | 86 | 175 | 0 | 0 | 0 | 0 | 21 | 11 | 5 | 4.19 |
| SP | Scherzer, M.Scherzer, Max >> | 29 | 2021 | R | 94 | 34 | 34 | 8 | 11 | 3.71 | .302 | 1.27 | 8.6 | 2.9 | 8.7 | 204.0 | 194 | 88 | 84 | 29 | 65 | 197 | 0 | 0 | 0 | 0 | 22 | 6 | 8 | 3.96 |
| SP | Santana, J.Santana, Johan >> | 27 | 2004 | L | 91 | 33 | 33 | 9 | 11 | 5.67 | .321 | 1.39 | 9.3 | 3.3 | 8.0 | 174.2 | 180 | 114 | 110 | 31 | 63 | 154 | 1 | 0 | 0 | 1 | 15 | 5 | 3 | 4.72 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 89 | 33 | 33 | 11 | 10 | 5.63 | .327 | 1.43 | 9.9 | 2.9 | 4.8 | 171.0 | 189 | 111 | 107 | 26 | 56 | 91 | 1 | 0 | 0 | 0 | 13 | 4 | 7 | 4.96 |
| SU | Betances, D.Betances, Dellin >> | 28 | 2014 | R | 98 | 77 | 0 | 6 | 7 | 2.47 | .293 | 1.21 | 6.4 | 4.6 | 8.0 | 83.2 | 59 | 25 | 23 | 6 | 42 | 74 | 0 | 9 | 3 | 0 | 0 | 3 | 2 | 3.78 |
| RP | Adams, M.Adams, Mike $$ >> | 31 | 2009 | R | 94 | 99 | 0 | 2 | 5 | 3.83 | .273 | 1.12 | 7.4 | 2.7 | 6.9 | 101.0 | 83 | 46 | 43 | 10 | 30 | 77 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 3.68 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2014 | L | 86 | 91 | 0 | 2 | 4 | 3.35 | .290 | 1.20 | 7.9 | 3.0 | 8.8 | 80.2 | 70 | 34 | 30 | 9 | 27 | 78 | 0 | 5 | 3 | 0 | 0 | 2 | 0 | 3.60 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 26 | 1983 | R | 81 | 78 | 0 | 6 | 5 | 3.87 | .288 | 1.19 | 7.8 | 3.0 | 5.3 | 88.1 | 76 | 42 | 38 | 10 | 29 | 52 | 0 | 2 | 4 | 0 | 0 | 2 | 1 | 4.35 |
| RP | Foulke, K.Foulke, Keith >> | 29 | 1999 | R | 77 | 58 | 0 | 5 | 4 | 5.35 | .324 | 1.38 | 8.7 | 3.7 | 6.5 | 69.0 | 67 | 42 | 41 | 15 | 28 | 50 | 0 | 3 | 0 | 0 | 0 | 4 | 0 | 5.77 |