| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 92 | 36 | 36 | 11 | 21 | 3.69 | .265 | 1.07 | 7.0 | 2.6 | 9.8 | 256.0 | 199 | 109 | 105 | 27 | 74 | 278 | 15 | 0 | 0 | 3 | 22 | 4 | 1 | 3.11 |
| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 100 | 35 | 35 | 15 | 12 | 3.28 | .296 | 1.23 | 7.7 | 3.4 | 9.2 | 208.1 | 179 | 77 | 76 | 19 | 78 | 213 | 1 | 0 | 0 | 1 | 24 | 6 | 0 | 3.35 |
| SP | Rogers, S.Rogers, Steve >> | 24 | 1973 | R | 41 | 34 | 34 | 16 | 14 | 3.94 | .303 | 1.27 | 8.0 | 3.4 | 5.2 | 237.2 | 211 | 109 | 104 | 24 | 90 | 137 | 11 | 0 | 0 | 2 | 18 | 9 | 3 | 4.41 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 73 | 32 | 32 | 11 | 13 | 4.72 | .318 | 1.37 | 8.8 | 3.5 | 5.7 | 196.1 | 191 | 108 | 103 | 25 | 77 | 124 | 3 | 0 | 0 | 0 | 14 | 7 | 3 | 4.68 |
| SP | Strasburg, S.Strasburg, Stephen # >> | 24 | 2013 | R | 38 | 25 | 25 | 9 | 12 | 4.80 | .322 | 1.40 | 9.5 | 3.2 | 9.1 | 140.2 | 148 | 78 | 75 | 12 | 49 | 141 | 1 | 0 | 0 | 1 | 15 | 3 | 0 | 3.21 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 90 | 84 | 0 | 8 | 1 | 2.76 | .249 | 0.97 | 5.3 | 3.4 | 5.3 | 150.0 | 89 | 48 | 46 | 11 | 56 | 89 | 0 | 10 | 4 | 0 | 0 | 4 | 3 | 3.97 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 75 | 66 | 0 | 4 | 4 | 3.20 | .305 | 1.30 | 7.8 | 3.9 | 9.5 | 76.0 | 66 | 30 | 27 | 6 | 33 | 80 | 0 | 9 | 1 | 0 | 0 | 1 | 3 | 3.26 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 71 | 46 | 0 | 4 | 1 | 3.05 | .250 | 0.98 | 7.0 | 1.9 | 8.4 | 62.0 | 48 | 21 | 21 | 7 | 13 | 58 | 0 | 5 | 0 | 0 | 0 | 1 | 0 | 3.27 |
| RP | Valdez, S.Valdez, Sergio >> | 28 | 1992 | R | 20 | 31 | 0 | 2 | 0 | 2.66 | .290 | 1.23 | 6.5 | 4.5 | 7.2 | 44.0 | 32 | 15 | 13 | 4 | 22 | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 4.09 |
| SP | Twitchell, W.Twitchell, Wayne >> | 29 | 1977 | R | 11 | 5 | 0 | 0 | 1 | 2.25 | .294 | 1.25 | 6.8 | 4.5 | 4.5 | 4.0 | 3 | 1 | 1 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.75 |