| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 88 | 36 | 36 | 9 | 16 | 4.75 | .323 | 1.42 | 10.4 | 2.4 | 9.0 | 182.0 | 210 | 100 | 96 | 23 | 49 | 181 | 0 | 0 | 0 | 0 | 8 | 1 | 3 | 3.48 |
| SP | Verlander, J.Verlander, Justin # >> | 28 | 2011 | R | 86 | 35 | 35 | 15 | 12 | 4.03 | .304 | 1.29 | 8.4 | 3.1 | 7.4 | 212.0 | 199 | 102 | 95 | 21 | 74 | 175 | 1 | 0 | 0 | 1 | 21 | 5 | 7 | 3.75 |
| SP | Wilson, E.Wilson, Earl # >> | 32 | 1966 | R | 35 | 34 | 34 | 6 | 17 | 5.62 | .347 | 1.56 | 10.6 | 3.5 | 6.0 | 166.2 | 196 | 109 | 104 | 27 | 64 | 111 | 0 | 0 | 0 | 0 | 13 | 6 | 4 | 5.04 |
| SP | Aguirre, H.Aguirre, Hank >> | 31 | 1962 | L | 30 | 33 | 33 | 0 | 12 | 6.64 | .357 | 1.66 | 11.1 | 3.8 | 6.0 | 127.1 | 157 | 101 | 94 | 22 | 54 | 85 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 5.21 |
| SP | Lolich, M.Lolich, Mickey # >> | 28 | 1968 | L | 15 | 26 | 24 | 2 | 8 | 6.06 | .358 | 1.63 | 11.2 | 3.6 | 7.3 | 108.1 | 134 | 77 | 73 | 19 | 43 | 88 | 0 | 0 | 0 | 0 | 1 | 4 | 3 | 4.96 |
| RP | Greene, S.Greene, Shane # >> | 30 | 2019 | R | 70 | 96 | 0 | 5 | 4 | 5.06 | .349 | 1.61 | 9.8 | 4.7 | 9.9 | 101.1 | 110 | 65 | 57 | 14 | 53 | 111 | 0 | 4 | 7 | 0 | 0 | 0 | 0 | 4.18 |
| RP | Saucier, K.Saucier, Kevin >> | 25 | 1981 | L | 48 | 118 | 0 | 6 | 3 | 4.93 | .306 | 1.31 | 6.7 | 5.2 | 4.1 | 87.2 | 65 | 50 | 48 | 8 | 50 | 40 | 0 | 3 | 0 | 0 | 0 | 1 | 4 | 5.03 |
| RP | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 46 | 82 | 0 | 5 | 9 | 3.72 | .281 | 1.17 | 7.5 | 3.1 | 5.7 | 113.2 | 94 | 52 | 47 | 15 | 39 | 71 | 0 | 15 | 5 | 0 | 0 | 0 | 5 | 4.50 |
| RP | Rondon, B.Rondon, Bruce # >> | 25 | 2016 | R | 39 | 78 | 0 | 3 | 5 | 5.42 | .366 | 1.72 | 8.8 | 6.8 | 8.8 | 79.2 | 77 | 48 | 48 | 7 | 60 | 77 | 0 | 4 | 5 | 0 | 0 | 1 | 1 | 4.52 |
| RP | Miller, S.Miller, Shelby >> | 33 | 2024 | R | 17 | 40 | 0 | 1 | 1 | 4.65 | .337 | 1.52 | 9.9 | 4.1 | 7.0 | 40.2 | 44 | 22 | 21 | 9 | 18 | 31 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 5.73 |
| RP | Melton, T.Melton, Troy >> | 24 | 2025 | R | 16 | 33 | 0 | 4 | 1 | 3.04 | .316 | 1.37 | 7.4 | 5.0 | 5.3 | 56.1 | 46 | 21 | 19 | 1 | 31 | 33 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 3.77 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 13 | 23 | 0 | 2 | 1 | 6.17 | .320 | 1.41 | 8.6 | 4.3 | 7.0 | 23.1 | 22 | 17 | 16 | 2 | 11 | 18 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.00 |
| SP | Rozema, D.Rozema, Dave # >> | 25 | 1981 | R | 6 | 56 | 0 | 13 | 2 | 4.73 | .324 | 1.42 | 9.5 | 3.3 | 4.3 | 154.0 | 163 | 88 | 81 | 17 | 56 | 73 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 4.62 |