| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 63 | 12 | 12 | 4 | 5 | 4.50 | .285 | 1.20 | 8.7 | 2.1 | 8.6 | 82.0 | 79 | 41 | 41 | 12 | 19 | 78 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 3.70 |
| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 64 | 12 | 12 | 5 | 5 | 3.17 | .270 | 1.10 | 7.2 | 2.7 | 7.8 | 76.2 | 61 | 29 | 27 | 6 | 23 | 66 | 1 | 0 | 0 | 0 | 8 | 1 | 0 | 3.24 |
| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 62 | 11 | 11 | 4 | 3 | 3.14 | .259 | 1.02 | 6.5 | 2.7 | 7.4 | 77.1 | 56 | 27 | 27 | 8 | 23 | 63 | 0 | 0 | 0 | 0 | 7 | 2 | 2 | 3.69 |
| SP | Paddack, C.Paddack, Chris >> | 23 | 2019 | R | 47 | 10 | 10 | 5 | 4 | 4.55 | .312 | 1.34 | 9.6 | 2.5 | 8.8 | 57.1 | 61 | 30 | 29 | 9 | 16 | 56 | 0 | 0 | 0 | 0 | 3 | 1 | 2 | 3.98 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 25 | 0 | 1 | 0 | 1.51 | .207 | 0.73 | 4.4 | 2.3 | 11.8 | 35.2 | 17 | 6 | 6 | 2 | 9 | 46 | 0 | 5 | 0 | 0 | 0 | 2 | 1 | 2.06 |
| RP | Lamet, D.Lamet, Dinelson >> | 27 | 2020 | R | 74 | 14 | 0 | 2 | 2 | 3.45 | .299 | 1.21 | 7.2 | 4.2 | 11.4 | 15.2 | 12 | 6 | 6 | 2 | 7 | 19 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 3.80 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 87 | 15 | 0 | 1 | 3 | 8.56 | .388 | 1.90 | 13.2 | 4.8 | 11.1 | 13.2 | 19 | 15 | 13 | 5 | 7 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7.15 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 58 | 4 | 0 | 0 | 0 | 0.00 | .286 | 1.20 | 6.0 | 6.0 | 6.0 | 3.1 | 2 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.67 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 69 | 6 | 0 | 0 | 0 | 2.84 | .321 | 1.26 | 10.5 | 1.5 | 10.5 | 6.1 | 7 | 2 | 2 | 0 | 1 | 7 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1.67 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 53 | 15 | 0 | 0 | 0 | 4.96 | .290 | 1.22 | 7.9 | 3.4 | 9.0 | 16.1 | 14 | 12 | 9 | 3 | 6 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.56 |