| SP | Arrieta, J.Arrieta, Jake >> | 28 | 2014 | R | 60 | 37 | 37 | 13 | 13 | 4.76 | .317 | 1.37 | 9.3 | 3.0 | 9.3 | 210.0 | 218 | 119 | 111 | 33 | 70 | 218 | 0 | 0 | 0 | 0 | 20 | 4 | 8 | 4.02 |
| SP | Imanaga, S.Imanaga, Shota >> | 31 | 2025 | L | 36 | 36 | 33 | 15 | 12 | 4.09 | .303 | 1.28 | 8.8 | 2.8 | 6.7 | 193.2 | 189 | 99 | 88 | 20 | 59 | 144 | 0 | 1 | 0 | 0 | 18 | 4 | 3 | 3.83 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 26 | 2016 | R | 56 | 36 | 36 | 11 | 13 | 4.80 | .327 | 1.43 | 10.1 | 2.8 | 5.6 | 187.1 | 209 | 106 | 100 | 31 | 59 | 116 | 0 | 0 | 0 | 0 | 18 | 5 | 4 | 4.94 |
| SP | Eckersley, D.Eckersley, Dennis # >> | 31 | 1985 | R | 38 | 33 | 33 | 10 | 9 | 5.52 | .330 | 1.46 | 11.0 | 2.2 | 6.1 | 190.2 | 233 | 118 | 117 | 33 | 46 | 129 | 0 | 0 | 0 | 0 | 14 | 3 | 0 | 4.67 |
| SP | Brown, M.Brown, Mordecai # >> | 31 | 1907 | R | 59 | 29 | 28 | 10 | 8 | 6.34 | .326 | 1.42 | 9.9 | 2.9 | 6.2 | 143.1 | 158 | 107 | 101 | 23 | 46 | 99 | 1 | 0 | 0 | 0 | 11 | 4 | 5 | 4.76 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 92 | 92 | 0 | 6 | 4 | 3.26 | .285 | 1.15 | 6.1 | 4.3 | 10.5 | 124.1 | 84 | 46 | 45 | 10 | 59 | 145 | 0 | 2 | 2 | 0 | 0 | 6 | 9 | 3.28 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 33 | 2021 | R | 100 | 74 | 0 | 8 | 10 | 3.59 | .290 | 1.21 | 6.3 | 4.7 | 9.8 | 77.2 | 54 | 31 | 31 | 7 | 40 | 84 | 0 | 41 | 3 | 0 | 0 | 1 | 4 | 3.60 |
| RP | Tepera, R.Tepera, Ryan >> | 33 | 2021 | R | 89 | 88 | 0 | 6 | 1 | 2.82 | .245 | 0.97 | 5.8 | 2.9 | 9.2 | 118.0 | 76 | 38 | 37 | 12 | 38 | 121 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 3.26 |
| RP | Miller, T.Miller, Tyson >> | 28 | 2024 | R | 66 | 77 | 0 | 1 | 2 | 4.24 | .295 | 1.23 | 8.6 | 2.5 | 6.4 | 93.1 | 89 | 47 | 44 | 12 | 26 | 66 | 0 | 1 | 4 | 0 | 0 | 2 | 0 | 4.16 |
| RP | Chavez, J.Chavez, Jesse >> | 35 | 2018 | R | 64 | 52 | 0 | 4 | 1 | 3.20 | .305 | 1.31 | 9.7 | 2.3 | 8.2 | 64.2 | 69 | 24 | 23 | 6 | 16 | 58 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 3.16 |
| RP | Wesneski, H.Wesneski, Hayden # >> | 24 | 2022 | R | 25 | 39 | 0 | 3 | 3 | 5.05 | .305 | 1.27 | 8.5 | 3.0 | 10.0 | 66.0 | 62 | 37 | 37 | 9 | 22 | 73 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 3.70 |