| SP | Martinez, C.Martinez, Carlos † >> | 25 | 2016 | R | 80 | 33 | 33 | 16 | 8 | 4.05 | .313 | 1.32 | 8.5 | 3.4 | 7.3 | 211.1 | 199 | 101 | 95 | 24 | 80 | 172 | 1 | 0 | 0 | 0 | 17 | 10 | 7 | 4.13 |
| SP | Hellickson, J.Hellickson, Jeremy # >> | 29 | 2016 | R | 82 | 32 | 32 | 11 | 12 | 3.82 | .318 | 1.37 | 9.4 | 3.0 | 6.8 | 195.2 | 203 | 90 | 83 | 23 | 65 | 147 | 0 | 0 | 0 | 0 | 18 | 6 | 4 | 4.12 |
| SP | Musgrove, J.Musgrove, Joseph >> | 23 | 2016 | R | 77 | 31 | 31 | 11 | 10 | 4.20 | .304 | 1.28 | 9.3 | 2.2 | 8.1 | 182.1 | 189 | 89 | 85 | 33 | 45 | 164 | 0 | 0 | 0 | 0 | 18 | 5 | 0 | 4.38 |
| SP | Velasquez, V.Velasquez, Vince # >> | 24 | 2016 | R | 64 | 29 | 29 | 15 | 6 | 4.25 | .309 | 1.30 | 8.6 | 3.1 | 9.9 | 163.0 | 156 | 78 | 77 | 21 | 56 | 179 | 0 | 0 | 0 | 0 | 14 | 7 | 6 | 3.64 |
| SP | Keuchel, D.Keuchel, Dallas # >> | 28 | 2016 | L | 63 | 25 | 23 | 10 | 10 | 4.37 | .301 | 1.26 | 8.7 | 2.7 | 7.1 | 152.1 | 147 | 81 | 74 | 21 | 45 | 120 | 2 | 0 | 1 | 0 | 12 | 5 | 4 | 4.20 |
| RP | Devenski, C.Devenski, Chris † >> | 25 | 2016 | R | 92 | 85 | 0 | 11 | 5 | 2.53 | .258 | 1.03 | 7.2 | 2.1 | 8.2 | 174.1 | 140 | 51 | 49 | 13 | 40 | 158 | 0 | 21 | 4 | 0 | 0 | 2 | 5 | 2.88 |
| RP | Peacock, B.Peacock, Brad † >> | 28 | 2016 | R | 84 | 67 | 0 | 7 | 3 | 1.83 | .270 | 1.10 | 5.8 | 4.1 | 7.7 | 137.1 | 88 | 30 | 28 | 9 | 63 | 117 | 0 | 19 | 3 | 0 | 0 | 1 | 4 | 3.55 |
| RP | Ogando, N.Ogando, Nefi >> | 27 | 2016 | R | 75 | 34 | 0 | 2 | 1 | 1.99 | .295 | 1.20 | 6.8 | 4.3 | 8.3 | 40.2 | 30 | 9 | 9 | 1 | 19 | 37 | 0 | 3 | 1 | 0 | 0 | 2 | 2 | 3.05 |
| RP | Feliz, M.Feliz, Michael >> | 23 | 2016 | R | 77 | 15 | 0 | 3 | 0 | 4.86 | .351 | 1.56 | 9.6 | 5.1 | 14.1 | 16.2 | 17 | 9 | 9 | 0 | 9 | 25 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 1.75 |