| SP | Kluber, C.Kluber, Corey # >> | 30 | 2016 | R | 97 | 33 | 33 | 9 | 16 | 4.14 | .302 | 1.27 | 8.8 | 2.6 | 10.4 | 226.0 | 222 | 117 | 104 | 25 | 65 | 262 | 2 | 0 | 0 | 0 | 20 | 6 | 5 | 3.06 |
| SP | Carrasco, C.Carrasco, Carlos # >> | 29 | 2016 | R | 86 | 33 | 33 | 12 | 11 | 4.28 | .323 | 1.39 | 9.9 | 2.6 | 9.0 | 201.2 | 222 | 101 | 96 | 30 | 58 | 202 | 0 | 0 | 0 | 0 | 18 | 8 | 4 | 3.92 |
| SP | Salazar, D.Salazar, Danny # >> | 26 | 2016 | R | 72 | 31 | 31 | 10 | 11 | 5.17 | .310 | 1.30 | 8.4 | 3.4 | 9.7 | 177.2 | 165 | 107 | 102 | 26 | 66 | 191 | 0 | 0 | 0 | 0 | 14 | 8 | 15 | 4.01 |
| SP | Chatwood, T.Chatwood, Tyler >> | 26 | 2016 | R | 53 | 29 | 29 | 7 | 11 | 5.06 | .339 | 1.50 | 9.7 | 3.8 | 7.4 | 172.2 | 186 | 105 | 97 | 28 | 73 | 142 | 0 | 0 | 0 | 0 | 15 | 7 | 7 | 4.86 |
| SP | Colon, B.Colon, Bartolo >> | 43 | 2016 | R | 60 | 19 | 19 | 11 | 2 | 3.88 | .303 | 1.28 | 9.7 | 1.8 | 6.9 | 118.1 | 127 | 52 | 51 | 13 | 24 | 90 | 0 | 0 | 0 | 0 | 9 | 3 | 0 | 3.59 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 100 | 103 | 0 | 1 | 3 | 2.58 | .261 | 1.02 | 7.8 | 1.5 | 12.0 | 80.1 | 69 | 23 | 23 | 7 | 13 | 107 | 0 | 3 | 4 | 0 | 0 | 3 | 2 | 2.06 |
| RP | Montgomery, M.Montgomery, Mike >> | 26 | 2016 | L | 76 | 92 | 0 | 3 | 3 | 1.98 | .266 | 1.06 | 6.6 | 3.0 | 7.1 | 72.2 | 53 | 16 | 16 | 3 | 24 | 57 | 0 | 9 | 3 | 0 | 0 | 2 | 3 | 3.04 |
| RP | Manship, J.Manship, Jeff >> | 31 | 2016 | R | 39 | 73 | 0 | 5 | 3 | 3.42 | .324 | 1.42 | 8.2 | 4.6 | 7.1 | 71.0 | 65 | 27 | 27 | 9 | 36 | 56 | 0 | 4 | 4 | 0 | 0 | 1 | 0 | 4.63 |
| RP | Clevinger, M.Clevinger, Mike † >> | 25 | 2016 | R | 35 | 73 | 0 | 9 | 7 | 3.23 | .276 | 1.14 | 6.8 | 3.4 | 8.2 | 100.1 | 76 | 37 | 36 | 11 | 38 | 91 | 0 | 11 | 2 | 0 | 0 | 1 | 1 | 3.78 |
| SP | Tomlin, J.Tomlin, Josh >> | 31 | 2016 | R | 60 | 9 | 0 | 2 | 3 | 9.90 | .434 | 2.00 | 16.2 | 1.8 | 9.0 | 10.0 | 18 | 11 | 11 | 4 | 2 | 10 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 7.70 |