| SP | Lackey, J.Lackey, John † >> | 38 | 2016 | R | 96 | 31 | 31 | 14 | 10 | 3.30 | .289 | 1.14 | 7.1 | 3.2 | 8.5 | 207.0 | 164 | 79 | 76 | 16 | 73 | 195 | 1 | 0 | 0 | 0 | 23 | 15 | 4 | 3.40 |
| SP | Santana, E.Santana, Ervin # >> | 33 | 2016 | R | 75 | 32 | 32 | 13 | 14 | 5.16 | .333 | 1.47 | 10.3 | 2.9 | 8.0 | 190.0 | 218 | 112 | 109 | 21 | 62 | 169 | 0 | 0 | 0 | 0 | 15 | 5 | 5 | 3.72 |
| SP | Shoemaker, M.Shoemaker, Matt >> | 29 | 2016 | R | 68 | 31 | 31 | 7 | 13 | 5.14 | .319 | 1.36 | 10.0 | 2.3 | 7.7 | 184.0 | 204 | 111 | 105 | 21 | 46 | 158 | 1 | 0 | 0 | 0 | 14 | 8 | 2 | 3.65 |
| SP | Richards, G.Richards, Garrett # >> | 28 | 2016 | R | 67 | 28 | 28 | 4 | 9 | 5.32 | .364 | 1.70 | 10.3 | 4.9 | 8.7 | 142.0 | 163 | 87 | 84 | 18 | 78 | 138 | 0 | 0 | 0 | 0 | 9 | 3 | 4 | 4.42 |
| CL | Bedrosian, C.Bedrosian, Cam † >> | 24 | 2016 | R | 88 | 51 | 0 | 2 | 3 | 3.59 | .306 | 1.26 | 7.1 | 4.4 | 9.8 | 47.2 | 37 | 19 | 19 | 5 | 23 | 51 | 0 | 33 | 4 | 0 | 0 | 3 | 2 | 3.87 |
| SU | Rodriguez, F.Rodriguez, Francisco >> | 34 | 2016 | R | 80 | 75 | 0 | 5 | 4 | 2.32 | .287 | 1.16 | 7.1 | 3.4 | 8.2 | 77.2 | 61 | 22 | 20 | 5 | 29 | 70 | 0 | 5 | 2 | 0 | 0 | 4 | 7 | 3.31 |
| RP | O'Day, D.O'Day, Darren >> | 34 | 2016 | R | 77 | 86 | 0 | 7 | 3 | 6.75 | .368 | 1.74 | 11.6 | 4.0 | 10.3 | 68.0 | 88 | 52 | 51 | 9 | 30 | 78 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 3.79 |
| RP | Valdez, J.Valdez, Jose >> | 26 | 2016 | R | 55 | 63 | 0 | 2 | 2 | 2.51 | .327 | 1.44 | 7.5 | 5.5 | 8.1 | 61.0 | 51 | 19 | 17 | 2 | 37 | 55 | 0 | 2 | 2 | 0 | 0 | 1 | 2 | 3.49 |
| RP | Estevez, C.Estevez, Carlos >> | 23 | 2016 | R | 46 | 55 | 0 | 3 | 5 | 4.55 | .319 | 1.37 | 9.1 | 3.2 | 8.7 | 61.1 | 62 | 33 | 31 | 5 | 22 | 59 | 0 | 1 | 2 | 0 | 0 | 2 | 5 | 3.31 |
| SP | Corbin, P.Corbin, Patrick >> | 26 | 2016 | L | 25 | 32 | 1 | 4 | 1 | 4.93 | .335 | 1.49 | 10.3 | 3.2 | 8.3 | 91.1 | 104 | 51 | 50 | 8 | 32 | 84 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 3.42 |