| SP | Bauer, T.Bauer, Trevor # >> | 25 | 2016 | R | 66 | 31 | 31 | 14 | 10 | 4.26 | .322 | 1.40 | 9.0 | 3.6 | 6.8 | 173.1 | 173 | 85 | 82 | 17 | 70 | 131 | 0 | 0 | 0 | 0 | 12 | 4 | 2 | 4.05 |
| SP | Garcia, J.Garcia, Jaime # >> | 30 | 2016 | L | 49 | 31 | 30 | 9 | 8 | 4.91 | .338 | 1.50 | 10.6 | 3.0 | 8.0 | 150.1 | 176 | 83 | 82 | 16 | 50 | 133 | 0 | 0 | 0 | 0 | 9 | 4 | 3 | 3.69 |
| SP | Wainwright, A.Wainwright, Adam # >> | 35 | 2016 | R | 38 | 29 | 28 | 9 | 12 | 4.89 | .318 | 1.37 | 8.7 | 3.6 | 7.9 | 136.1 | 132 | 74 | 74 | 22 | 55 | 119 | 0 | 0 | 0 | 0 | 12 | 4 | 1 | 4.65 |
| SP | Bettis, C.Bettis, Chad # >> | 27 | 2016 | R | 37 | 24 | 23 | 3 | 14 | 6.91 | .358 | 1.65 | 11.6 | 3.3 | 7.5 | 100.1 | 129 | 79 | 77 | 15 | 37 | 83 | 0 | 0 | 0 | 0 | 7 | 2 | 3 | 4.46 |
| RP | Ottavino, A.Ottavino, Adam >> | 30 | 2016 | R | 98 | 78 | 0 | 5 | 2 | 2.35 | .250 | 0.94 | 5.5 | 3.0 | 10.9 | 115.0 | 70 | 33 | 30 | 3 | 38 | 139 | 0 | 5 | 2 | 0 | 0 | 7 | 10 | 2.10 |
| RP | Siegrist, K.Siegrist, Kevin >> | 26 | 2016 | L | 88 | 80 | 0 | 6 | 8 | 3.36 | .318 | 1.36 | 8.2 | 4.1 | 10.9 | 96.1 | 87 | 37 | 36 | 6 | 44 | 116 | 0 | 9 | 4 | 0 | 0 | 4 | 5 | 2.90 |
| RP | Salas, F.Salas, Fernando >> | 31 | 2016 | R | 74 | 54 | 0 | 2 | 1 | 3.44 | .305 | 1.30 | 8.6 | 3.2 | 9.3 | 65.1 | 62 | 25 | 25 | 5 | 23 | 67 | 0 | 5 | 2 | 0 | 0 | 1 | 1 | 3.05 |
| SP | Wacha, M.Wacha, Michael # >> | 24 | 2016 | R | 30 | 44 | 0 | 2 | 8 | 5.37 | .344 | 1.55 | 9.9 | 4.2 | 8.0 | 110.2 | 121 | 69 | 66 | 11 | 51 | 98 | 0 | 6 | 2 | 0 | 0 | 2 | 3 | 3.96 |