| SP | Perez, O.Perez, Oliver >> | 28 | 2004 | L | 98 | 33 | 33 | 16 | 12 | 3.46 | .269 | 1.05 | 6.4 | 3.1 | 9.2 | 228.2 | 162 | 91 | 88 | 35 | 79 | 234 | 7 | 0 | 0 | 2 | 20 | 11 | 2 | 4.13 |
| SP | Peavy, J.Peavy, Jake † >> | 28 | 2005 | R | 98 | 33 | 33 | 20 | 6 | 2.57 | .269 | 1.07 | 6.9 | 2.8 | 9.7 | 256.0 | 196 | 73 | 73 | 24 | 79 | 277 | 9 | 0 | 0 | 3 | 26 | 7 | 4 | 3.06 |
| RP | Walker, K.Walker, Kevin >> | 33 | 2000 | L | 96 | 75 | 0 | 7 | 3 | 2.19 | .241 | 0.94 | 6.2 | 2.3 | 9.5 | 98.2 | 68 | 29 | 24 | 7 | 25 | 103 | 0 | 3 | 3 | 0 | 0 | 1 | 1 | 2.62 |
| RP | Aquino, G.Aquino, Greg >> | 31 | 2004 | R | 82 | 41 | 0 | 1 | 1 | 4.01 | .326 | 1.43 | 9.0 | 4.1 | 7.7 | 42.2 | 42 | 24 | 19 | 6 | 19 | 36 | 0 | 1 | 1 | 0 | 0 | 1 | 3 | 4.57 |
| RP | Hensley, C.Hensley, Clay >> | 30 | 2005 | R | 82 | 26 | 0 | 2 | 0 | 4.41 | .320 | 1.38 | 9.8 | 2.9 | 5.6 | 34.2 | 37 | 17 | 17 | 6 | 11 | 21 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 5.12 |
| SP | LeBlanc, W.LeBlanc, Wade >> | 25 | 2009 | L | 53 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Mujica, E.Mujica, Edward >> | 25 | 2009 | R | 25 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Thatcher, J.Thatcher, Joe >> | 28 | 2009 | L | 51 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Gregerson, L.Gregerson, Luke >> | 25 | 2009 | R | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| CL | Meredith, C.Meredith, Cla + >> | 26 | 2006 | R | 97 | 63 | 0 | 3 | 15 | 4.41 | .285 | 1.16 | 8.3 | 2.2 | 5.0 | 65.1 | 60 | 35 | 32 | 12 | 16 | 36 | 0 | 35 | 5 | 0 | 0 | 2 | 0 | 5.12 |
| SU | Fikac, J.Fikac, Jeremy >> | 34 | 2001 | R | 93 | 45 | 0 | 2 | 0 | 2.19 | .225 | 0.81 | 5.9 | 1.5 | 6.6 | 49.1 | 32 | 13 | 12 | 7 | 8 | 36 | 0 | 4 | 5 | 0 | 0 | 3 | 0 | 4.06 |