| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 88 | 33 | 33 | 10 | 17 | 5.11 | .322 | 1.41 | 9.3 | 3.4 | 10.1 | 179.2 | 185 | 111 | 102 | 36 | 68 | 200 | 2 | 0 | 0 | 0 | 14 | 3 | 2 | 4.57 |
| SP | Verlander, J.Verlander, Justin # >> | 31 | 2012 | R | 64 | 33 | 33 | 8 | 12 | 5.89 | .322 | 1.41 | 8.4 | 4.3 | 8.4 | 188.0 | 175 | 127 | 123 | 36 | 90 | 175 | 1 | 0 | 0 | 0 | 11 | 3 | 1 | 5.11 |
| SP | Pierce, B.Pierce, Billy >> | 29 | 1955 | L | 61 | 32 | 32 | 8 | 11 | 5.42 | .331 | 1.47 | 10.0 | 3.3 | 6.2 | 177.2 | 197 | 117 | 107 | 39 | 64 | 121 | 1 | 0 | 0 | 0 | 13 | 3 | 0 | 5.63 |
| SP | Fister, D.Fister, Doug # >> | 30 | 2012 | R | 38 | 32 | 31 | 12 | 13 | 5.12 | .331 | 1.46 | 9.7 | 3.4 | 5.9 | 174.0 | 188 | 106 | 99 | 34 | 66 | 115 | 0 | 0 | 0 | 0 | 13 | 4 | 4 | 5.43 |
| CL | Villarreal, B.Villarreal, Brayan >> | 27 | 2012 | R | 81 | 80 | 0 | 4 | 8 | 4.77 | .323 | 1.42 | 8.1 | 4.8 | 7.9 | 88.2 | 79 | 49 | 47 | 16 | 47 | 77 | 0 | 25 | 9 | 0 | 0 | 1 | 12 | 5.25 |
| SU | Labine, C.Labine, Clem >> | 29 | 1953 | R | 68 | 73 | 0 | 5 | 4 | 4.28 | .307 | 1.30 | 8.2 | 3.5 | 5.2 | 122.0 | 111 | 68 | 58 | 22 | 47 | 70 | 0 | 10 | 4 | 0 | 0 | 4 | 3 | 5.45 |
| RP | Milliken, B.Milliken, Bob >> | 29 | 1953 | R | 70 | 75 | 0 | 8 | 8 | 5.39 | .328 | 1.44 | 8.6 | 4.3 | 5.8 | 177.0 | 169 | 116 | 106 | 36 | 85 | 115 | 0 | 1 | 5 | 0 | 0 | 5 | 6 | 5.87 |
| RP | Chouinard, B.Chouinard, Bobby >> | 27 | 1999 | R | 56 | 90 | 0 | 5 | 4 | 3.69 | .339 | 1.52 | 8.8 | 5.0 | 6.7 | 112.1 | 109 | 63 | 46 | 13 | 62 | 83 | 0 | 2 | 2 | 0 | 0 | 2 | 1 | 4.74 |
| RP | Dotel, O.Dotel, Octavio >> | 41 | 2012 | R | 30 | 73 | 0 | 6 | 2 | 4.03 | .303 | 1.30 | 8.9 | 2.8 | 7.8 | 76.0 | 75 | 42 | 34 | 10 | 24 | 66 | 0 | 0 | 3 | 0 | 0 | 0 | 1 | 3.92 |