| SP | Verlander, J.Verlander, Justin >> | 39 | 2022 | R | 99 | 33 | 33 | 12 | 15 | 3.64 | .274 | 1.12 | 7.5 | 2.5 | 8.6 | 215.0 | 180 | 88 | 87 | 28 | 60 | 206 | 7 | 0 | 0 | 2 | 18 | 3 | 3 | 3.66 |
| SP | Javier, C.Javier, Cristian >> | 25 | 2022 | R | 93 | 33 | 33 | 12 | 10 | 3.80 | .280 | 1.15 | 6.2 | 4.1 | 9.8 | 189.2 | 131 | 82 | 80 | 25 | 87 | 205 | 1 | 0 | 0 | 0 | 17 | 3 | 3 | 3.98 |
| SP | Marichal, J.Marichal, Juan >> | 28 | 1965 | R | 79 | 32 | 32 | 9 | 19 | 4.57 | .304 | 1.29 | 8.5 | 3.1 | 6.9 | 207.0 | 196 | 108 | 105 | 37 | 71 | 158 | 10 | 0 | 0 | 0 | 15 | 4 | 1 | 4.88 |
| SP | Bosman, D.Bosman, Dick >> | 27 | 1969 | R | 69 | 33 | 30 | 8 | 13 | 5.18 | .335 | 1.48 | 10.1 | 3.2 | 5.1 | 184.1 | 207 | 113 | 106 | 34 | 66 | 104 | 1 | 0 | 0 | 0 | 10 | 5 | 2 | 5.43 |
| RP | Pressly, R.Pressly, Ryan >> | 33 | 2022 | R | 92 | 86 | 0 | 9 | 2 | 3.06 | .239 | 0.90 | 5.2 | 3.0 | 10.2 | 111.2 | 64 | 38 | 38 | 15 | 37 | 126 | 0 | 8 | 1 | 0 | 0 | 4 | 0 | 3.59 |
| RP | Neris, H.Neris, Hector >> | 33 | 2022 | R | 73 | 46 | 0 | 4 | 2 | 2.48 | .252 | 0.99 | 5.2 | 3.8 | 10.0 | 54.1 | 31 | 17 | 15 | 5 | 23 | 60 | 0 | 5 | 0 | 0 | 0 | 1 | 5 | 3.31 |
| RP | Montero, R.Montero, Rafael >> | 31 | 2022 | R | 76 | 26 | 0 | 2 | 1 | 3.54 | .243 | 0.96 | 6.1 | 2.6 | 7.7 | 28.0 | 19 | 11 | 11 | 4 | 8 | 24 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Stanek, R.Stanek, Ryne >> | 30 | 2022 | R | 55 | 22 | 0 | 0 | 2 | 6.17 | .352 | 1.54 | 8.2 | 5.9 | 11.0 | 23.1 | 21 | 16 | 16 | 4 | 15 | 28 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 5.04 |
| SP | Cuellar, M.Cuellar, Mike >> | 34 | 1969 | L | 60 | 30 | 0 | 4 | 0 | 5.55 | .335 | 1.49 | 9.3 | 4.1 | 4.9 | 107.0 | 110 | 69 | 66 | 15 | 49 | 58 | 0 | 0 | 1 | 0 | 0 | 3 | 1 | 5.20 |