| SP | Cortes Jr., N.Cortes Jr., Nestor $$ >> | 35 | 2022 | L | 94 | 33 | 33 | 13 | 14 | 4.06 | .297 | 1.24 | 8.0 | 3.1 | 6.9 | 186.0 | 165 | 96 | 84 | 24 | 65 | 143 | 1 | 0 | 0 | 1 | 15 | 6 | 1 | 4.28 |
| SP | May, D.May, Dustin † $$ >> | 32 | 2022 | R | 92 | 32 | 32 | 14 | 9 | 3.07 | .300 | 1.26 | 7.2 | 4.2 | 6.9 | 187.2 | 150 | 67 | 64 | 16 | 87 | 144 | 0 | 0 | 0 | 0 | 16 | 4 | 0 | 4.03 |
| SP | Ohtani, S.Ohtani, Shohei # $$ >> | 35 | 2022 | R | 88 | 33 | 33 | 9 | 14 | 4.37 | .305 | 1.29 | 8.7 | 3.0 | 8.7 | 181.1 | 174 | 98 | 88 | 23 | 60 | 174 | 0 | 0 | 0 | 0 | 17 | 5 | 11 | 3.81 |
| SP | Skubal, T.Skubal, Tarik # >> | 33 | 2022 | L | 68 | 33 | 26 | 6 | 11 | 6.01 | .346 | 1.54 | 10.8 | 3.1 | 5.8 | 121.1 | 145 | 86 | 81 | 30 | 42 | 78 | 0 | 3 | 0 | 0 | 5 | 6 | 0 | 6.12 |
| RP | Clarkson, D.Clarkson, Dave $$ >> | 29 | 2023 | R | 93 | 91 | 0 | 6 | 6 | 3.23 | .297 | 1.26 | 7.1 | 4.2 | 9.8 | 117.0 | 92 | 43 | 42 | 13 | 55 | 127 | 0 | 2 | 1 | 0 | 0 | 1 | 5 | 3.71 |
| RP | Jones-Drew, B.Jones-Drew, Bill # $$ >> | 28 | 2024 | R | 93 | 93 | 0 | 6 | 5 | 3.21 | .274 | 1.10 | 7.4 | 2.5 | 8.3 | 126.0 | 104 | 46 | 45 | 15 | 35 | 116 | 0 | 1 | 3 | 0 | 0 | 4 | 2 | 3.63 |
| RP | Patterson, J.Patterson, Joe $$ >> | 26 | 2024 | R | 85 | 74 | 0 | 4 | 8 | 3.65 | .288 | 1.17 | 7.7 | 2.9 | 9.3 | 103.2 | 88 | 43 | 42 | 13 | 33 | 106 | 0 | 4 | 2 | 0 | 0 | 5 | 4 | 3.69 |
| CL | Izzo, M.Izzo, Mickey † $$ >> | 29 | 2024 | R | 97 | 72 | 0 | 3 | 1 | 2.63 | .293 | 1.21 | 6.8 | 4.1 | 10.8 | 82.0 | 62 | 31 | 24 | 5 | 37 | 98 | 0 | 31 | 0 | 0 | 0 | 3 | 4 | 2.87 |
| SU | Diaz, A.Diaz, Alexis $$ >> | 33 | 2022 | R | 96 | 79 | 0 | 3 | 0 | 1.93 | .243 | 0.95 | 4.9 | 3.7 | 9.3 | 93.1 | 51 | 23 | 20 | 6 | 38 | 96 | 0 | 2 | 5 | 0 | 0 | 1 | 2 | 3.03 |