| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 69 | 35 | 35 | 10 | 14 | 4.26 | .312 | 1.33 | 8.9 | 3.1 | 8.5 | 202.2 | 199 | 98 | 96 | 30 | 70 | 190 | 0 | 0 | 0 | 0 | 19 | 7 | 2 | 4.19 |
| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 62 | 35 | 35 | 13 | 15 | 4.05 | .302 | 1.27 | 7.3 | 4.1 | 9.4 | 200.0 | 163 | 93 | 90 | 26 | 90 | 208 | 1 | 0 | 0 | 1 | 20 | 6 | 8 | 4.05 |
| SP | Darvish, Y.Darvish, Yu # >> | 35 | 2022 | R | 71 | 33 | 33 | 12 | 15 | 4.95 | .325 | 1.42 | 9.9 | 2.8 | 7.7 | 182.0 | 201 | 109 | 100 | 46 | 57 | 156 | 0 | 0 | 0 | 0 | 19 | 5 | 4 | 5.59 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 97 | 97 | 0 | 4 | 3 | 3.13 | .271 | 1.12 | 5.7 | 4.4 | 9.9 | 126.1 | 80 | 48 | 44 | 12 | 61 | 139 | 0 | 2 | 2 | 0 | 0 | 0 | 3 | 3.48 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 87 | 87 | 0 | 4 | 4 | 3.31 | .256 | 1.00 | 5.5 | 3.6 | 8.5 | 108.2 | 66 | 41 | 40 | 12 | 43 | 102 | 0 | 5 | 2 | 0 | 0 | 3 | 4 | 3.83 |
| RP | Meredith, C.Meredith, Cla # >> | 23 | 2006 | R | 75 | 69 | 0 | 2 | 1 | 4.99 | .299 | 1.27 | 9.0 | 2.4 | 6.8 | 70.1 | 70 | 39 | 39 | 11 | 19 | 53 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.39 |
| RP | Lamet, D.Lamet, Dinelson >> | 27 | 2020 | R | 70 | 51 | 0 | 5 | 2 | 2.74 | .274 | 1.08 | 6.8 | 3.0 | 9.9 | 101.2 | 76 | 33 | 31 | 10 | 34 | 111 | 0 | 1 | 0 | 0 | 0 | 5 | 0 | 3.25 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 63 | 31 | 0 | 1 | 1 | 3.03 | .319 | 1.35 | 7.3 | 5.1 | 10.7 | 32.2 | 26 | 11 | 11 | 3 | 18 | 38 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.72 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 53 | 28 | 0 | 1 | 0 | 1.24 | .227 | 0.85 | 6.3 | 1.5 | 10.5 | 36.1 | 25 | 8 | 5 | 4 | 6 | 42 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.69 |