| SP | Darvish, Y.Darvish, Yu # >> | 35 | 2022 | R | 64 | 36 | 36 | 6 | 16 | 5.32 | .322 | 1.39 | 9.7 | 2.8 | 9.5 | 191.1 | 205 | 119 | 113 | 27 | 60 | 201 | 0 | 0 | 0 | 0 | 10 | 7 | 5 | 3.79 |
| SP | Paddack, C.Paddack, Chris # >> | 23 | 2019 | R | 59 | 34 | 34 | 6 | 10 | 4.52 | .318 | 1.37 | 8.9 | 3.4 | 9.7 | 149.1 | 148 | 78 | 75 | 16 | 56 | 161 | 0 | 0 | 0 | 0 | 3 | 5 | 3 | 3.46 |
| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 64 | 33 | 33 | 8 | 10 | 4.62 | .337 | 1.51 | 8.0 | 5.7 | 8.8 | 192.2 | 170 | 99 | 99 | 15 | 121 | 188 | 0 | 0 | 0 | 0 | 16 | 3 | 10 | 3.99 |
| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 69 | 26 | 26 | 8 | 8 | 4.44 | .321 | 1.41 | 8.3 | 4.4 | 8.0 | 146.0 | 134 | 74 | 72 | 18 | 72 | 129 | 1 | 0 | 0 | 1 | 10 | 1 | 0 | 4.34 |
| RP | Lamet, D.Lamet, Dinelson >> | 27 | 2020 | R | 73 | 84 | 0 | 7 | 8 | 3.94 | .302 | 1.27 | 7.6 | 3.8 | 9.0 | 171.1 | 144 | 78 | 75 | 24 | 73 | 171 | 0 | 8 | 5 | 0 | 0 | 5 | 3 | 4.19 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 79 | 0 | 9 | 4 | 2.70 | .279 | 1.16 | 6.9 | 3.6 | 9.3 | 103.1 | 79 | 35 | 31 | 7 | 41 | 107 | 0 | 4 | 5 | 0 | 0 | 0 | 1 | 3.00 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 88 | 71 | 0 | 3 | 3 | 2.52 | .272 | 1.09 | 6.1 | 3.7 | 9.1 | 93.0 | 63 | 28 | 26 | 4 | 38 | 94 | 0 | 11 | 2 | 0 | 0 | 3 | 4 | 2.86 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 63 | 53 | 0 | 7 | 2 | 3.09 | .262 | 1.06 | 8.1 | 1.6 | 8.4 | 58.1 | 52 | 21 | 20 | 6 | 10 | 54 | 0 | 7 | 3 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Martinez, P.Martinez, Pedro >> | 25 | 1993 | L | 32 | 37 | 0 | 2 | 3 | 3.46 | .282 | 1.15 | 6.5 | 3.9 | 5.5 | 39.0 | 28 | 16 | 15 | 6 | 17 | 24 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 5.15 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 55 | 30 | 0 | 2 | 2 | 1.98 | .264 | 1.05 | 6.5 | 3.0 | 7.5 | 36.1 | 26 | 8 | 8 | 4 | 12 | 30 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.86 |