| SP | Samardzija, J.Samardzija, Jeff # >> | 29 | 2014 | R | 64 | 35 | 35 | 14 | 14 | 5.10 | .311 | 1.35 | 10.0 | 2.1 | 6.3 | 256.0 | 285 | 151 | 145 | 50 | 60 | 178 | 5 | 0 | 0 | 0 | 16 | 2 | 7 | 4.88 |
| SP | Duchscherer, J.Duchscherer, Justin # >> | 31 | 2008 | R | 46 | 35 | 35 | 11 | 10 | 4.93 | .320 | 1.38 | 9.2 | 3.2 | 6.2 | 228.1 | 233 | 131 | 125 | 32 | 82 | 156 | 2 | 0 | 0 | 1 | 18 | 8 | 7 | 4.64 |
| SP | Harden, R.Harden, Rich # >> | 24 | 2005 | R | 38 | 35 | 35 | 12 | 13 | 5.25 | .342 | 1.54 | 9.5 | 4.3 | 5.9 | 209.0 | 221 | 128 | 122 | 27 | 100 | 137 | 0 | 0 | 0 | 0 | 14 | 5 | 7 | 4.88 |
| SP | Bassitt, C.Bassitt, Chris >> | 32 | 2021 | R | 24 | 24 | 24 | 8 | 7 | 5.07 | .343 | 1.53 | 10.4 | 3.3 | 10.0 | 135.0 | 156 | 81 | 76 | 22 | 50 | 150 | 1 | 0 | 0 | 0 | 6 | 5 | 1 | 4.12 |
| RP | Eckersley, D.Eckersley, Dennis >> | 35 | 1989 | R | 88 | 89 | 0 | 15 | 3 | 2.42 | .240 | 0.93 | 6.4 | 2.1 | 7.2 | 126.2 | 89 | 35 | 34 | 11 | 29 | 101 | 0 | 3 | 3 | 0 | 0 | 2 | 0 | 3.27 |
| RP | Doolittle, S.Doolittle, Sean >> | 27 | 2014 | L | 83 | 88 | 0 | 8 | 2 | 2.89 | .283 | 1.14 | 7.5 | 2.9 | 10.5 | 99.2 | 82 | 35 | 32 | 9 | 32 | 115 | 0 | 0 | 3 | 0 | 0 | 4 | 0 | 2.95 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 74 | 91 | 0 | 9 | 2 | 2.53 | .267 | 1.07 | 5.8 | 3.9 | 8.5 | 92.1 | 59 | 27 | 26 | 5 | 40 | 87 | 0 | 12 | 2 | 0 | 0 | 2 | 0 | 3.18 |
| RP | Miller, M.Miller, Mason >> | 25 | 2024 | R | 68 | 64 | 0 | 6 | 4 | 2.06 | .269 | 1.08 | 5.8 | 3.9 | 9.6 | 48.0 | 31 | 11 | 11 | 5 | 21 | 51 | 0 | 12 | 1 | 0 | 0 | 1 | 3 | 3.60 |
| RP | Madson, R.Madson, Ryan >> | 37 | 2017 | R | 61 | 36 | 0 | 2 | 4 | 2.20 | .271 | 1.12 | 7.7 | 2.6 | 8.7 | 28.2 | 24 | 7 | 7 | 1 | 8 | 27 | 0 | 7 | 2 | 0 | 0 | 0 | 0 | 2.39 |
| RP | Abad, F.Abad, Fernando >> | 28 | 2014 | L | 55 | 40 | 0 | 2 | 2 | 2.38 | .260 | 1.06 | 7.2 | 2.4 | 7.9 | 41.2 | 33 | 12 | 11 | 2 | 11 | 36 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 2.68 |
| SP | Ontiveros, S.Ontiveros, Steve >> | 33 | 1994 | R | 23 | 33 | 33 | 5 | 4 | 6.23 | .346 | 1.56 | 10.4 | 3.7 | 6.4 | 138.2 | 160 | 100 | 96 | 22 | 57 | 98 | 0 | 0 | 0 | 0 | 1 | 3 | 5 | 4.96 |