| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 87 | 35 | 35 | 13 | 16 | 3.94 | .291 | 1.20 | 7.8 | 3.0 | 7.9 | 246.2 | 213 | 114 | 108 | 28 | 83 | 215 | 7 | 0 | 0 | 3 | 19 | 8 | 2 | 3.84 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 57 | 34 | 34 | 11 | 18 | 5.22 | .318 | 1.38 | 9.8 | 2.6 | 8.8 | 238.0 | 258 | 139 | 138 | 44 | 70 | 233 | 3 | 0 | 0 | 1 | 11 | 5 | 5 | 4.39 |
| SP | Greinke, Z.Greinke, Zack >> | 36 | 2019 | R | 65 | 27 | 26 | 11 | 8 | 3.63 | .300 | 1.24 | 8.1 | 3.1 | 6.6 | 173.2 | 156 | 73 | 70 | 22 | 59 | 127 | 1 | 0 | 0 | 1 | 14 | 8 | 2 | 4.35 |
| CL | Ramirez, N.Ramirez, Noe >> | 31 | 2021 | R | 50 | 62 | 0 | 5 | 3 | 3.92 | .285 | 1.18 | 7.4 | 3.2 | 6.5 | 62.0 | 51 | 27 | 27 | 12 | 22 | 45 | 0 | 36 | 5 | 0 | 0 | 1 | 3 | 5.18 |
| SU | Ginkel, K.Ginkel, Kevin >> | 29 | 2023 | R | 26 | 45 | 0 | 1 | 2 | 3.86 | .296 | 1.24 | 7.0 | 4.3 | 10.2 | 44.1 | 34 | 20 | 19 | 6 | 21 | 50 | 0 | 3 | 2 | 0 | 0 | 1 | 1 | 4.00 |
| RP | Medders, B.Medders, Brandon >> | 25 | 2005 | R | 14 | 90 | 0 | 5 | 5 | 3.84 | .289 | 1.19 | 7.0 | 3.7 | 7.9 | 96.0 | 75 | 41 | 41 | 11 | 39 | 84 | 0 | 3 | 2 | 0 | 0 | 3 | 1 | 4.05 |
| RP | Nelson, K.Nelson, Kyle >> | 25 | 2022 | L | 10 | 58 | 0 | 2 | 3 | 4.91 | .331 | 1.48 | 9.2 | 4.3 | 4.7 | 58.2 | 59 | 35 | 32 | 9 | 28 | 30 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 5.43 |
| RP | Chouinard, B.Chouinard, Bobby >> | 27 | 1999 | R | 7 | 43 | 0 | 1 | 3 | 6.07 | .333 | 1.48 | 9.4 | 3.9 | 3.3 | 46.0 | 48 | 31 | 31 | 8 | 20 | 17 | 0 | 1 | 2 | 0 | 0 | 1 | 2 | 5.89 |
| RP | Perez, O.Perez, Oliver >> | 33 | 2014 | L | 6 | 39 | 0 | 1 | 1 | 2.29 | .248 | 0.94 | 5.3 | 3.2 | 8.5 | 39.1 | 23 | 10 | 10 | 2 | 14 | 37 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.00 |