| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 98 | 35 | 35 | 18 | 11 | 3.31 | .292 | 1.20 | 7.8 | 3.1 | 9.4 | 239.1 | 207 | 99 | 88 | 27 | 81 | 250 | 2 | 0 | 0 | 2 | 22 | 8 | 3 | 3.49 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 26 | 2016 | R | 60 | 35 | 35 | 12 | 12 | 3.97 | .309 | 1.33 | 8.6 | 3.3 | 6.6 | 222.1 | 213 | 104 | 98 | 27 | 82 | 163 | 1 | 0 | 0 | 0 | 21 | 3 | 7 | 4.26 |
| SP | Lester, J.Lester, Jon # >> | 32 | 2016 | L | 49 | 35 | 34 | 14 | 8 | 4.70 | .313 | 1.34 | 9.6 | 2.5 | 6.9 | 212.2 | 225 | 114 | 111 | 26 | 59 | 162 | 0 | 0 | 0 | 0 | 19 | 7 | 4 | 4.00 |
| SP | Imanaga, S.Imanaga, Shota >> | 31 | 2025 | L | 39 | 24 | 24 | 7 | 8 | 3.87 | .315 | 1.31 | 9.6 | 2.2 | 6.0 | 142.0 | 151 | 63 | 61 | 15 | 35 | 94 | 0 | 0 | 0 | 0 | 11 | 10 | 1 | 4.00 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 94 | 93 | 0 | 7 | 4 | 2.16 | .244 | 0.96 | 4.9 | 3.8 | 10.5 | 120.2 | 65 | 30 | 29 | 9 | 51 | 140 | 0 | 4 | 5 | 0 | 0 | 1 | 6 | 2.94 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 33 | 2021 | R | 100 | 74 | 0 | 0 | 9 | 2.78 | .264 | 1.07 | 6.7 | 3.0 | 9.7 | 81.0 | 60 | 25 | 25 | 7 | 27 | 87 | 0 | 37 | 5 | 0 | 0 | 0 | 1 | 2.98 |
| RP | Tepera, R.Tepera, Ryan >> | 33 | 2021 | R | 86 | 79 | 0 | 10 | 4 | 2.06 | .220 | 0.84 | 4.1 | 3.6 | 8.6 | 100.2 | 45 | 25 | 23 | 9 | 40 | 96 | 0 | 5 | 0 | 0 | 0 | 0 | 4 | 3.45 |
| RP | Hodge, P.Hodge, Porter >> | 23 | 2024 | R | 78 | 58 | 0 | 3 | 4 | 3.72 | .290 | 1.19 | 6.0 | 4.8 | 9.0 | 65.1 | 43 | 27 | 27 | 3 | 35 | 65 | 0 | 2 | 2 | 0 | 0 | 2 | 1 | 3.31 |
| SP | Chatwood, T.Chatwood, Tyler >> | 28 | 2018 | R | 4 | 13 | 1 | 1 | 4 | 7.71 | .409 | 2.01 | 11.7 | 6.6 | 5.7 | 30.1 | 39 | 28 | 26 | 8 | 22 | 19 | 0 | 1 | 3 | 0 | 0 | 2 | 3 | 7.60 |