| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 96 | 25 | 25 | 14 | 6 | 2.87 | .265 | 1.06 | 7.1 | 2.4 | 9.7 | 163.0 | 129 | 55 | 52 | 17 | 43 | 176 | 0 | 0 | 0 | 0 | 19 | 4 | 4 | 3.06 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 61 | 24 | 24 | 9 | 8 | 4.99 | .328 | 1.44 | 9.3 | 3.6 | 6.7 | 119.0 | 123 | 68 | 66 | 23 | 48 | 88 | 0 | 0 | 0 | 0 | 5 | 3 | 3 | 5.32 |
| SP | Imanaga, S.Imanaga, Shota # >> | 31 | 2025 | L | 39 | 22 | 22 | 4 | 9 | 4.63 | .305 | 1.30 | 9.6 | 2.1 | 7.0 | 114.2 | 122 | 62 | 59 | 21 | 27 | 89 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 4.60 |
| SP | Darvish, Y.Darvish, Yu >> | 32 | 2019 | R | 31 | 22 | 22 | 4 | 8 | 4.39 | .316 | 1.36 | 7.9 | 4.4 | 10.0 | 104.2 | 91 | 53 | 51 | 10 | 51 | 115 | 0 | 0 | 0 | 0 | 1 | 3 | 4 | 3.60 |
| SP | Hammel, J.Hammel, Jason # >> | 32 | 2014 | R | 35 | 19 | 18 | 5 | 5 | 5.42 | .310 | 1.33 | 9.5 | 2.5 | 8.5 | 96.1 | 101 | 58 | 58 | 23 | 27 | 91 | 1 | 1 | 0 | 0 | 7 | 2 | 2 | 5.13 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 33 | 2021 | R | 100 | 60 | 0 | 3 | 2 | 2.16 | .251 | 0.99 | 4.8 | 4.2 | 9.9 | 87.2 | 46 | 23 | 21 | 8 | 41 | 96 | 0 | 4 | 1 | 0 | 0 | 1 | 3 | 3.44 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 93 | 62 | 0 | 4 | 3 | 3.31 | .302 | 1.27 | 5.2 | 6.3 | 9.4 | 73.1 | 42 | 27 | 27 | 5 | 51 | 76 | 0 | 12 | 2 | 0 | 0 | 2 | 5 | 3.99 |
| RP | Hodge, P.Hodge, Porter >> | 23 | 2024 | R | 77 | 44 | 0 | 3 | 2 | 2.35 | .277 | 1.15 | 6.6 | 3.8 | 10.3 | 57.1 | 42 | 15 | 15 | 4 | 24 | 65 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 2.89 |
| RP | Strop, P.Strop, Pedro # >> | 31 | 2016 | R | 66 | 36 | 0 | 0 | 4 | 5.18 | .317 | 1.39 | 9.4 | 3.3 | 8.6 | 41.2 | 43 | 24 | 24 | 4 | 15 | 39 | 0 | 8 | 5 | 0 | 0 | 0 | 6 | 3.46 |
| RP | Miller, T.Miller, Tyson >> | 28 | 2024 | R | 64 | 15 | 0 | 1 | 2 | 2.41 | .291 | 1.23 | 9.0 | 2.5 | 9.0 | 18.2 | 18 | 5 | 5 | 2 | 5 | 18 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.28 |
| RP | Thielbar, C.Thielbar, Caleb >> | 38 | 2025 | L | 50 | 12 | 0 | 0 | 1 | 3.77 | .306 | 1.26 | 7.7 | 3.9 | 5.8 | 14.1 | 12 | 6 | 6 | 1 | 6 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.14 |
| RP | Wesneski, H.Wesneski, Hayden >> | 24 | 2022 | R | 26 | 17 | 0 | 3 | 3 | 4.50 | .294 | 1.25 | 8.7 | 2.6 | 8.4 | 28.0 | 27 | 18 | 14 | 7 | 8 | 26 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.25 |
| SP | Steele, J.Steele, Justin >> | 28 | 2024 | L | 20 | 20 | 0 | 3 | 5 | 4.39 | .324 | 1.39 | 7.9 | 4.6 | 9.5 | 84.0 | 74 | 41 | 41 | 11 | 43 | 89 | 0 | 0 | 0 | 0 | 0 | 4 | 1 | 4.26 |