| SP | Scherzer, M.Scherzer, Max # >> | 37 | 2021 | R | 99 | 37 | 37 | 13 | 9 | 4.98 | .323 | 1.40 | 9.1 | 3.4 | 9.4 | 217.0 | 220 | 123 | 120 | 35 | 83 | 227 | 0 | 0 | 0 | 0 | 17 | 7 | 0 | 4.25 |
| SP | Martinez, P.Martinez, Pedro # >> | 26 | 1997 | R | 93 | 36 | 36 | 13 | 12 | 5.01 | .323 | 1.41 | 9.0 | 3.7 | 9.3 | 249.2 | 249 | 146 | 139 | 33 | 103 | 258 | 10 | 0 | 0 | 0 | 14 | 5 | 2 | 3.95 |
| SP | Perez, P.Perez, Pascual # >> | 31 | 1988 | R | 77 | 36 | 36 | 14 | 16 | 4.74 | .309 | 1.33 | 9.3 | 2.6 | 6.5 | 235.1 | 244 | 133 | 124 | 40 | 68 | 171 | 5 | 0 | 0 | 0 | 20 | 4 | 4 | 4.68 |
| SP | Strasburg, S.Strasburg, Stephen >> | 24 | 2013 | R | 44 | 32 | 31 | 13 | 12 | 5.64 | .365 | 1.70 | 11.3 | 4.0 | 8.5 | 169.0 | 212 | 115 | 106 | 24 | 75 | 159 | 0 | 0 | 0 | 0 | 12 | 4 | 4 | 4.37 |
| SP | Rogers, S.Rogers, Steve # >> | 24 | 1973 | R | 41 | 26 | 26 | 7 | 12 | 6.31 | .379 | 1.81 | 10.6 | 5.7 | 5.5 | 148.1 | 174 | 113 | 104 | 16 | 94 | 91 | 0 | 0 | 0 | 0 | 11 | 4 | 10 | 5.16 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 95 | 0 | 10 | 7 | 4.38 | .294 | 1.23 | 8.9 | 2.2 | 10.0 | 123.1 | 122 | 62 | 60 | 20 | 30 | 136 | 0 | 6 | 9 | 0 | 0 | 2 | 0 | 3.68 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 86 | 80 | 0 | 7 | 4 | 2.76 | .271 | 1.11 | 7.7 | 2.4 | 6.1 | 114.0 | 97 | 40 | 35 | 9 | 30 | 77 | 0 | 15 | 4 | 0 | 0 | 0 | 3 | 3.46 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 69 | 47 | 0 | 5 | 2 | 3.99 | .323 | 1.43 | 7.7 | 5.3 | 9.4 | 49.2 | 42 | 22 | 22 | 11 | 29 | 51 | 0 | 8 | 0 | 0 | 0 | 0 | 1 | 5.61 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 66 | 21 | 0 | 0 | 1 | 1.63 | .272 | 1.08 | 7.0 | 3.0 | 9.3 | 27.2 | 21 | 5 | 5 | 3 | 9 | 28 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 3.48 |
| SP | Schatzeder, D.Schatzeder, Dan >> | 30 | 1984 | L | 14 | 33 | 0 | 7 | 0 | 4.87 | .328 | 1.43 | 9.5 | 3.5 | 5.8 | 88.2 | 93 | 49 | 48 | 15 | 34 | 57 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 5.18 |