| SP | Mussina, M.Mussina, Mike >> | 37 | 2005 | R | 51 | 5 | 5 | 2 | 2 | 4.13 | .295 | 1.22 | 9.6 | 1.7 | 5.6 | 32.2 | 34 | 17 | 15 | 3 | 6 | 20 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 3.63 |
| SP | Bedard, E.Bedard, Erik >> | 26 | 2005 | L | 63 | 5 | 5 | 1 | 2 | 2.87 | .309 | 1.34 | 9.0 | 3.2 | 7.3 | 31.1 | 31 | 14 | 10 | 3 | 11 | 25 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 3.71 |
| SP | Towers, J.Towers, Josh >> | 28 | 2005 | R | 50 | 4 | 4 | 1 | 2 | 6.45 | .287 | 1.21 | 9.0 | 2.0 | 4.9 | 22.1 | 22 | 16 | 16 | 3 | 5 | 12 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 4.36 |
| RP | Benitez, A.Benitez, Armando >> | 33 | 2005 | R | 67 | 13 | 0 | 1 | 0 | 2.08 | .264 | 1.08 | 6.2 | 3.5 | 4.2 | 13.0 | 9 | 3 | 3 | 0 | 5 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.23 |
| RP | Schilling, C.Schilling, Curt >> | 39 | 2005 | R | 28 | 8 | 0 | 1 | 1 | 3.12 | .316 | 1.38 | 10.1 | 3.4 | 10.1 | 8.2 | 9 | 3 | 3 | 1 | 3 | 9 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.50 |
| RP | DuBose, E.DuBose, Eric >> | 29 | 2005 | L | 35 | 16 | 0 | 0 | 0 | 4.30 | .389 | 1.77 | 10.9 | 5.8 | 6.4 | 14.2 | 17 | 7 | 7 | 0 | 9 | 10 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.93 |
| SP | Cabrera, D.Cabrera, Daniel >> | 24 | 2005 | R | 66 | 5 | 0 | 2 | 0 | 4.70 | .418 | 2.15 | 13.2 | 6.6 | 3.6 | 15.1 | 22 | 8 | 8 | 1 | 11 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.27 |