| SP | Rasner, D.Rasner, Darrell >> | 25 | 2006 | R | 87 | 10 | 10 | 1 | 2 | 4.19 | .254 | 0.98 | 7.3 | 1.5 | 4.6 | 43.0 | 35 | 20 | 20 | 2 | 7 | 22 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 3.21 |
| SP | Karstens, J.Karstens, Jeff >> | 24 | 2006 | R | 81 | 10 | 10 | 6 | 1 | 2.95 | .275 | 1.14 | 7.8 | 2.5 | 5.6 | 58.0 | 50 | 20 | 19 | 6 | 16 | 36 | 0 | 0 | 0 | 0 | 6 | 0 | 1 | 3.93 |
| SP | Hernandez, O.Hernandez, Orlando >> | 41 | 2006 | R | 77 | 10 | 10 | 1 | 3 | 5.51 | .382 | 1.84 | 11.0 | 5.5 | 8.4 | 49.0 | 60 | 31 | 30 | 6 | 30 | 46 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 4.61 |
| SP | Contreras, J.Contreras, Jose >> | 35 | 2006 | R | 81 | 9 | 9 | 5 | 4 | 3.53 | .282 | 1.13 | 8.6 | 1.7 | 7.0 | 63.2 | 60 | 26 | 25 | 8 | 12 | 49 | 0 | 0 | 0 | 0 | 6 | 3 | 1 | 3.81 |
| SP | Wang, C.Wang, Chien-Ming >> | 26 | 2006 | R | 63 | 6 | 5 | 1 | 3 | 5.85 | .345 | 1.55 | 11.3 | 2.8 | 5.1 | 32.1 | 40 | 25 | 21 | 4 | 10 | 18 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 4.53 |
| RP | Rivera, M.Rivera, Mariano >> | 37 | 2006 | R | 91 | 24 | 0 | 2 | 2 | 2.50 | .245 | 0.94 | 7.3 | 1.3 | 8.0 | 36.0 | 29 | 10 | 10 | 4 | 5 | 32 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.17 |
| RP | Pinto, R.Pinto, Renyel >> | 24 | 2006 | L | 56 | 25 | 0 | 2 | 2 | 5.68 | .387 | 1.89 | 11.2 | 6.1 | 7.6 | 25.1 | 31 | 16 | 16 | 3 | 17 | 21 | 0 | 2 | 2 | 0 | 0 | 0 | 3 | 4.92 |
| RP | Gaudin, C.Gaudin, Chad >> | 23 | 2006 | R | 57 | 17 | 0 | 2 | 1 | 2.28 | .317 | 1.39 | 7.8 | 5.1 | 6.7 | 23.2 | 20 | 6 | 6 | 1 | 13 | 17 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 3.78 |
| RP | Proctor, S.Proctor, Scott >> | 29 | 2006 | R | 86 | 22 | 0 | 1 | 0 | 3.86 | .292 | 1.14 | 7.7 | 2.6 | 8.1 | 21.0 | 18 | 9 | 9 | 4 | 6 | 19 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 4.81 |
| SP | Pettitte, A.Pettitte, Andy >> | 34 | 2006 | L | 52 | 8 | 0 | 2 | 1 | 5.40 | .344 | 1.58 | 12.5 | 2.1 | 6.9 | 13.1 | 18 | 8 | 8 | 2 | 3 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.15 |