| SP | Beckett, J.Beckett, Josh >> | 26 | 2006 | R | 82 | 10 | 10 | 1 | 5 | 5.16 | .338 | 1.48 | 10.8 | 2.6 | 6.1 | 59.1 | 71 | 39 | 34 | 5 | 17 | 40 | 0 | 0 | 0 | 0 | 5 | 3 | 2 | 3.76 |
| SP | Willis, D.Willis, Dontrelle >> | 24 | 2006 | L | 58 | 10 | 10 | 1 | 7 | 8.06 | .361 | 1.69 | 11.8 | 3.5 | 5.5 | 51.1 | 67 | 51 | 46 | 10 | 20 | 31 | 1 | 0 | 0 | 0 | 2 | 0 | 2 | 5.51 |
| SP | Burnett, A.Burnett, A.J. # >> | 29 | 2006 | R | 73 | 9 | 9 | 1 | 4 | 6.30 | .367 | 1.72 | 11.3 | 4.1 | 5.0 | 50.0 | 63 | 45 | 35 | 6 | 23 | 28 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 4.88 |
| RP | Grilli, J.Grilli, Jason >> | 30 | 2006 | R | 54 | 30 | 0 | 0 | 2 | 4.50 | .343 | 1.53 | 9.6 | 4.2 | 5.4 | 30.0 | 32 | 17 | 15 | 3 | 14 | 18 | 0 | 0 | 3 | 0 | 0 | 1 | 1 | 4.60 |
| RP | Dempster, R.Dempster, Ryan >> | 29 | 2006 | R | 45 | 28 | 0 | 3 | 3 | 4.40 | .317 | 1.36 | 9.0 | 3.5 | 7.7 | 28.2 | 28 | 18 | 14 | 3 | 11 | 24 | 0 | 2 | 1 | 0 | 0 | 1 | 3 | 3.96 |
| SP | Johnson, J.Johnson, Josh >> | 22 | 2006 | R | 84 | 8 | 8 | 4 | 1 | 3.54 | .279 | 1.12 | 8.1 | 2.1 | 7.5 | 48.1 | 43 | 20 | 19 | 4 | 11 | 40 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 3.23 |
| SP | Sanchez, A.Sanchez, Anibal >> | 22 | 2006 | R | 91 | 6 | 6 | 3 | 2 | 5.03 | .366 | 1.65 | 9.9 | 5.1 | 5.1 | 39.1 | 43 | 22 | 22 | 1 | 22 | 22 | 0 | 0 | 0 | 0 | 2 | 3 | 1 | 4.13 |
| RP | Tankersley, T.Tankersley, Taylor >> | 23 | 2006 | L | 68 | 31 | 0 | 1 | 0 | 3.86 | .364 | 1.71 | 8.6 | 7.0 | 11.3 | 23.1 | 22 | 12 | 10 | 2 | 18 | 29 | 0 | 2 | 0 | 0 | 0 | 0 | 4 | 3.96 |
| RP | Petit, Y.Petit, Yusmeiro >> | 22 | 2006 | R | 6 | 18 | 0 | 2 | 1 | 4.62 | .296 | 1.22 | 9.0 | 2.2 | 7.6 | 25.1 | 25 | 14 | 13 | 2 | 6 | 21 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.20 |
| SP | Nolasco, R.Nolasco, Ricky >> | 24 | 2006 | R | 51 | 5 | 1 | 0 | 1 | 2.38 | .244 | 0.88 | 6.5 | 1.6 | 5.7 | 11.1 | 8 | 3 | 3 | 0 | 2 | 7 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 2.55 |
| RP | Hoffman, T.Hoffman, Trevor >> | 39 | 2006 | R | 94 | 11 | 0 | 0 | 0 | 1.56 | .257 | 1.04 | 8.5 | 1.1 | 7.9 | 17.1 | 16 | 3 | 3 | 1 | 2 | 15 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.35 |