| SP | Jimenez, U.Jimenez, Ubaldo >> | 26 | 2010 | R | 97 | 8 | 8 | 5 | 2 | 2.34 | .282 | 1.14 | 7.4 | 3.0 | 7.4 | 57.2 | 47 | 15 | 15 | 3 | 19 | 47 | 0 | 0 | 0 | 0 | 7 | 2 | 3 | 3.14 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 82 | 7 | 7 | 1 | 3 | 6.03 | .338 | 1.53 | 9.0 | 4.9 | 8.4 | 31.1 | 31 | 22 | 21 | 4 | 17 | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.45 |
| SP | Dickey, R.Dickey, R.A. >> | 36 | 2010 | R | 77 | 7 | 7 | 1 | 2 | 5.92 | .360 | 1.68 | 11.6 | 3.6 | 6.9 | 38.0 | 49 | 27 | 25 | 4 | 15 | 29 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 4.03 |
| SP | Francis, J.Francis, Jeff >> | 29 | 2010 | L | 41 | 4 | 4 | 1 | 1 | 2.45 | .327 | 1.45 | 8.6 | 4.5 | 5.3 | 22.0 | 21 | 6 | 6 | 1 | 11 | 13 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 3.91 |
| RP | Reynolds, M.Reynolds, Matt >> | 25 | 2010 | L | 98 | 19 | 0 | 2 | 1 | 2.19 | .267 | 1.09 | 6.4 | 3.8 | 7.5 | 24.2 | 17 | 6 | 6 | 0 | 10 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.58 |
| RP | Rhodes, A.Rhodes, Arthur >> | 41 | 2010 | L | 93 | 16 | 0 | 1 | 0 | 1.40 | .216 | 0.83 | 6.2 | 1.4 | 9.0 | 19.1 | 13 | 4 | 3 | 3 | 3 | 19 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.53 |
| RP | Ramirez, R.Ramirez, Ramon >> | 29 | 2010 | R | 78 | 12 | 0 | 3 | 1 | 1.98 | .268 | 1.10 | 6.2 | 4.2 | 4.2 | 13.2 | 9 | 3 | 3 | 1 | 6 | 6 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.46 |
| RP | Lopez, J.Lopez, Javier >> | 33 | 2010 | L | 70 | 8 | 0 | 0 | 0 | 3.24 | .306 | 1.32 | 10.1 | 2.3 | 5.6 | 8.1 | 9 | 3 | 3 | 1 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.13 |
| RP | Nieve, F.Nieve, Fernando >> | 28 | 2010 | R | 56 | 8 | 0 | 0 | 1 | 2.35 | .258 | 1.04 | 7.7 | 2.6 | 10.3 | 7.2 | 6 | 2 | 2 | 1 | 2 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.43 |
| CL | Fuentes, B.Fuentes, Brian >> | 35 | 2010 | L | 95 | 12 | 0 | 1 | 1 | 3.77 | .317 | 1.26 | 7.7 | 3.9 | 5.1 | 14.1 | 12 | 6 | 6 | 0 | 6 | 8 | 0 | 6 | 2 | 0 | 0 | 2 | 1 | 3.57 |