| SP | Weaver, J.Weaver, Jered >> | 28 | 2010 | R | 98 | 9 | 9 | 1 | 6 | 9.61 | .408 | 2.02 | 12.3 | 5.9 | 11.3 | 44.0 | 60 | 47 | 47 | 7 | 29 | 55 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 4.68 |
| SP | Santana, E.Santana, Ervin >> | 27 | 2010 | R | 59 | 9 | 9 | 0 | 7 | 8.62 | .431 | 2.28 | 15.1 | 5.4 | 7.1 | 47.0 | 79 | 49 | 45 | 6 | 28 | 37 | 0 | 0 | 0 | 0 | 2 | 0 | 3 | 4.87 |
| SP | Lackey, J.Lackey, John # >> | 32 | 2010 | R | 36 | 8 | 8 | 1 | 6 | 7.60 | .405 | 2.02 | 15.0 | 3.2 | 6.8 | 45.0 | 75 | 40 | 38 | 7 | 16 | 34 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 4.64 |
| SP | Moseley, D.Moseley, Dustin >> | 29 | 2010 | R | 36 | 8 | 8 | 0 | 2 | 6.10 | .396 | 1.97 | 13.1 | 4.6 | 6.7 | 31.0 | 45 | 22 | 21 | 3 | 16 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.32 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 98 | 18 | 0 | 2 | 2 | 4.91 | .319 | 1.40 | 9.0 | 4.0 | 9.0 | 25.2 | 25 | 14 | 14 | 3 | 11 | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.88 |
| RP | Thompson, R.Thompson, Rich >> | 26 | 2010 | R | 96 | 20 | 0 | 1 | 0 | 2.25 | .244 | 0.97 | 7.0 | 1.7 | 8.2 | 32.0 | 25 | 9 | 8 | 0 | 6 | 29 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1.75 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 92 | 18 | 0 | 1 | 1 | 4.30 | .274 | 1.09 | 8.2 | 1.6 | 6.3 | 23.0 | 21 | 13 | 11 | 2 | 4 | 16 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.39 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 28 | 2010 | R | 83 | 14 | 0 | 1 | 1 | 4.30 | .302 | 1.30 | 10.3 | 1.9 | 11.6 | 14.2 | 16 | 7 | 7 | 0 | 3 | 18 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 1.07 |
| RP | Walden, J.Walden, Jordan >> | 22 | 2010 | R | 71 | 10 | 0 | 0 | 0 | 1.38 | .304 | 1.31 | 6.9 | 4.8 | 7.6 | 13.0 | 10 | 3 | 2 | 0 | 7 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2.92 |
| RP | Contreras, J.Contreras, Jose >> | 39 | 2010 | R | 70 | 8 | 0 | 0 | 1 | 1.08 | .324 | 1.32 | 6.8 | 5.6 | 12.4 | 8.1 | 6 | 2 | 1 | 0 | 5 | 11 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.50 |
| RP | Jepsen, K.Jepsen, Kevin >> | 26 | 2010 | R | 56 | 7 | 0 | 0 | 0 | 5.40 | .359 | 1.68 | 10.1 | 5.6 | 14.6 | 8.1 | 9 | 5 | 5 | 2 | 5 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.88 |