| SP | Bonderman, J.Bonderman, Jeremy >> | 24 | 2006 | R | 78 | 10 | 10 | 2 | 5 | 5.55 | .354 | 1.61 | 10.9 | 3.7 | 5.9 | 58.1 | 70 | 40 | 36 | 12 | 24 | 38 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 5.72 |
| SP | Robertson, N.Robertson, Nate >> | 29 | 2006 | L | 73 | 9 | 9 | 3 | 3 | 4.58 | .330 | 1.41 | 9.3 | 3.4 | 7.8 | 59.0 | 61 | 33 | 30 | 12 | 22 | 51 | 0 | 0 | 0 | 0 | 5 | 4 | 1 | 5.24 |
| SP | Verlander, J.Verlander, Justin >> | 23 | 2006 | R | 70 | 10 | 8 | 3 | 5 | 5.14 | .361 | 1.67 | 11.4 | 3.7 | 8.3 | 49.0 | 62 | 34 | 28 | 10 | 20 | 45 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 5.10 |
| SP | Maroth, M.Maroth, Mike >> | 29 | 2006 | L | 30 | 10 | 7 | 1 | 3 | 3.51 | .329 | 1.35 | 7.6 | 4.6 | 6.0 | 33.1 | 28 | 13 | 13 | 5 | 17 | 22 | 0 | 1 | 0 | 0 | 0 | 4 | 0 | 5.55 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 96 | 23 | 0 | 0 | 0 | 1.61 | .270 | 1.04 | 6.4 | 2.9 | 9.0 | 28.0 | 20 | 5 | 5 | 1 | 9 | 28 | 0 | 1 | 1 | 0 | 0 | 2 | 2 | 2.64 |
| RP | Rodney, F.Rodney, Fernando >> | 29 | 2006 | R | 90 | 25 | 0 | 1 | 0 | 2.70 | .252 | 1.01 | 6.9 | 2.4 | 8.3 | 26.2 | 20 | 8 | 8 | 1 | 7 | 24 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 2.46 |
| RP | Cordero, F.Cordero, Francisco >> | 31 | 2006 | R | 72 | 16 | 0 | 0 | 1 | 3.38 | .341 | 1.50 | 10.0 | 4.0 | 9.5 | 18.2 | 20 | 7 | 7 | 0 | 8 | 19 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 2.39 |
| RP | Ledezma, W.Ledezma, Wilfredo >> | 25 | 2006 | L | 54 | 31 | 0 | 4 | 3 | 2.54 | .303 | 1.31 | 8.7 | 3.2 | 7.4 | 28.1 | 27 | 11 | 8 | 0 | 10 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.43 |
| RP | Novoa, R.Novoa, Roberto >> | 27 | 2006 | R | 49 | 17 | 0 | 1 | 1 | 3.98 | .299 | 1.28 | 7.7 | 4.1 | 8.6 | 20.1 | 17 | 9 | 9 | 1 | 9 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 3.10 |
| SP | Weaver, J.Weaver, Jeff >> | 30 | 2006 | R | 32 | 12 | 3 | 0 | 3 | 3.47 | .299 | 1.26 | 8.1 | 3.3 | 5.7 | 49.1 | 44 | 19 | 19 | 7 | 18 | 31 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 4.76 |