| SP | Verlander, J.Verlander, Justin >> | 27 | 2010 | R | 91 | 7 | 7 | 3 | 2 | 2.61 | .255 | 1.01 | 6.7 | 2.5 | 8.3 | 51.2 | 38 | 17 | 15 | 4 | 14 | 47 | 1 | 0 | 0 | 0 | 5 | 1 | 1 | 3.06 |
| SP | Jurrjens, J.Jurrjens, Jair # >> | 24 | 2010 | R | 44 | 7 | 7 | 3 | 3 | 4.01 | .354 | 1.59 | 10.7 | 3.9 | 7.1 | 42.2 | 50 | 25 | 19 | 4 | 18 | 33 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 4.10 |
| SP | Mazzaro, V.Mazzaro, Vin >> | 23 | 2010 | R | 35 | 7 | 7 | 0 | 2 | 5.29 | .366 | 1.71 | 9.3 | 6.1 | 5.0 | 34.0 | 35 | 23 | 20 | 3 | 23 | 19 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 5.15 |
| SP | Porcello, R.Porcello, Rick >> | 21 | 2010 | R | 29 | 7 | 7 | 3 | 4 | 4.20 | .286 | 1.18 | 8.4 | 2.2 | 7.0 | 45.0 | 42 | 21 | 21 | 7 | 11 | 35 | 0 | 0 | 0 | 0 | 4 | 1 | 3 | 4.27 |
| SP | Lopez, R.Lopez, Rodrigo >> | 35 | 2010 | R | 29 | 5 | 5 | 1 | 2 | 5.92 | .354 | 1.64 | 9.8 | 5.3 | 7.5 | 24.1 | 26 | 16 | 16 | 4 | 14 | 20 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 5.25 |
| RP | Gutierrez, J.Gutierrez, Juan >> | 27 | 2010 | R | 50 | 16 | 0 | 4 | 1 | 1.59 | .313 | 1.37 | 7.4 | 5.3 | 4.5 | 22.2 | 18 | 7 | 4 | 0 | 13 | 11 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.77 |
| RP | Heilman, A.Heilman, Aaron >> | 32 | 2010 | R | 49 | 16 | 0 | 1 | 0 | 3.80 | .312 | 1.31 | 9.0 | 3.0 | 6.0 | 21.1 | 21 | 9 | 9 | 3 | 7 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.67 |
| RP | Cordero, F.Cordero, Francisco >> | 35 | 2010 | R | 47 | 11 | 0 | 0 | 0 | 4.85 | .381 | 1.77 | 9.7 | 6.2 | 4.8 | 13.0 | 14 | 9 | 7 | 2 | 9 | 7 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 6.23 |
| RP | Rodney, F.Rodney, Fernando >> | 33 | 2010 | R | 34 | 13 | 0 | 0 | 2 | 3.09 | .364 | 1.71 | 9.0 | 7.4 | 4.9 | 11.2 | 11 | 5 | 4 | 1 | 9 | 6 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.55 |
| RP | Gaudin, C.Gaudin, Chad >> | 27 | 2010 | R | 30 | 6 | 0 | 0 | 0 | 7.94 | .452 | 2.29 | 18.0 | 5.4 | 10.8 | 5.2 | 10 | 6 | 5 | 0 | 3 | 6 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.00 |