| SP | Halladay, R.Halladay, Roy >> | 33 | 2010 | R | 92 | 8 | 8 | 3 | 5 | 4.44 | .295 | 1.25 | 9.5 | 1.9 | 7.4 | 52.2 | 55 | 30 | 26 | 7 | 11 | 43 | 4 | 0 | 0 | 0 | 4 | 0 | 0 | 3.73 |
| SP | Marcum, S.Marcum, Shaun >> | 29 | 2010 | R | 86 | 7 | 7 | 3 | 3 | 4.69 | .313 | 1.34 | 9.9 | 2.3 | 6.5 | 40.1 | 44 | 21 | 21 | 6 | 10 | 29 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 4.33 |
| SP | Carpenter, C.Carpenter, Chris >> | 35 | 2010 | R | 84 | 7 | 7 | 3 | 1 | 3.30 | .265 | 1.08 | 7.8 | 2.0 | 7.0 | 46.1 | 40 | 18 | 17 | 1 | 10 | 36 | 1 | 0 | 0 | 0 | 4 | 0 | 2 | 2.37 |
| SP | Romero, R.Romero, Ricky >> | 25 | 2010 | L | 74 | 6 | 6 | 1 | 1 | 6.34 | .364 | 1.71 | 12.4 | 3.4 | 6.2 | 32.2 | 44 | 23 | 23 | 3 | 12 | 22 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 3.97 |
| RP | Purcey, D.Purcey, David >> | 28 | 2010 | L | 78 | 18 | 0 | 2 | 1 | 3.80 | .354 | 1.64 | 8.1 | 6.9 | 7.7 | 21.1 | 19 | 9 | 9 | 0 | 16 | 18 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.57 |
| RP | League, B.League, Brandon >> | 27 | 2010 | R | 74 | 15 | 0 | 2 | 0 | 5.12 | .266 | 1.09 | 6.6 | 3.3 | 5.2 | 19.1 | 14 | 11 | 11 | 2 | 7 | 11 | 0 | 1 | 2 | 0 | 0 | 0 | 5 | 4.32 |
| RP | Dessens, E.Dessens, Elmer >> | 39 | 2010 | R | 68 | 16 | 0 | 1 | 0 | 3.15 | .277 | 1.10 | 7.7 | 2.3 | 6.8 | 20.0 | 17 | 7 | 7 | 1 | 5 | 15 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 3.05 |
| RP | Batista, M.Batista, Miguel >> | 39 | 2010 | R | 59 | 12 | 0 | 1 | 1 | 3.12 | .316 | 1.38 | 8.5 | 4.2 | 5.8 | 17.1 | 16 | 6 | 6 | 0 | 8 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.12 |
| RP | Frasor, J.Frasor, Jason >> | 33 | 2010 | R | 54 | 6 | 0 | 1 | 0 | 0.00 | .267 | 1.09 | 6.4 | 3.9 | 12.9 | 7.1 | 5 | 0 | 0 | 0 | 3 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.43 |
| RP | Schlichting, T.Schlichting, Travis >> | 25 | 2010 | R | 53 | 7 | 0 | 0 | 0 | 0.00 | .200 | 0.75 | 3.0 | 4.0 | 4.0 | 9.1 | 3 | 0 | 0 | 0 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.44 |
| RP | Janssen, C.Janssen, Casey >> | 29 | 2010 | R | 42 | 7 | 0 | 0 | 0 | 4.50 | .333 | 1.50 | 10.1 | 3.4 | 7.9 | 8.0 | 9 | 4 | 4 | 2 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.63 |