| SP | Zambrano, C.Zambrano, Carlos >> | 25 | 2006 | R | 90 | 10 | 10 | 6 | 1 | 3.11 | .296 | 1.25 | 7.2 | 4.1 | 7.6 | 66.2 | 53 | 23 | 23 | 5 | 30 | 56 | 0 | 0 | 0 | 0 | 7 | 1 | 3 | 3.70 |
| SP | Maddux, G.Maddux, Greg # >> | 40 | 2006 | R | 75 | 9 | 9 | 2 | 4 | 4.97 | .315 | 1.38 | 10.3 | 2.2 | 5.7 | 54.1 | 62 | 30 | 30 | 4 | 13 | 34 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 3.43 |
| SU | Wuertz, M.Wuertz, Michael >> | 28 | 2006 | R | 82 | 22 | 0 | 0 | 0 | 2.31 | .271 | 1.11 | 6.7 | 3.5 | 7.8 | 23.1 | 17 | 6 | 6 | 0 | 9 | 20 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.43 |
| RP | Aardsma, D.Aardsma, David >> | 25 | 2006 | R | 84 | 25 | 0 | 5 | 2 | 1.99 | .240 | 0.95 | 4.6 | 4.1 | 7.3 | 31.2 | 16 | 7 | 7 | 1 | 14 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.16 |
| RP | Correia, K.Correia, Kevin >> | 26 | 2006 | R | 79 | 20 | 0 | 2 | 2 | 3.00 | .294 | 1.21 | 6.8 | 4.1 | 5.6 | 24.0 | 18 | 9 | 8 | 1 | 11 | 15 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 3.79 |
| RP | Borowski, J.Borowski, Joe >> | 35 | 2006 | R | 64 | 14 | 0 | 0 | 1 | 3.00 | .368 | 1.58 | 8.3 | 6.0 | 6.8 | 12.0 | 11 | 7 | 4 | 2 | 8 | 9 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 6.17 |