| SP | Sabathia, C.Sabathia, CC >> | 26 | 2006 | L | 93 | 10 | 10 | 6 | 2 | 2.82 | .297 | 1.22 | 8.9 | 2.2 | 5.6 | 79.2 | 78 | 28 | 25 | 3 | 19 | 49 | 5 | 0 | 0 | 1 | 7 | 4 | 3 | 3.13 |
| SP | Sowers, J.Sowers, Jeremy >> | 23 | 2006 | L | 80 | 10 | 10 | 8 | 2 | 3.13 | .282 | 1.18 | 8.5 | 2.1 | 4.6 | 72.0 | 68 | 27 | 25 | 7 | 17 | 37 | 1 | 0 | 0 | 0 | 8 | 0 | 0 | 3.94 |
| SP | Westbrook, J.Westbrook, Jake >> | 29 | 2006 | R | 41 | 9 | 9 | 3 | 4 | 6.84 | .400 | 1.98 | 14.4 | 3.4 | 5.4 | 50.0 | 80 | 38 | 38 | 7 | 19 | 30 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 4.82 |
| SP | Colon, B.Colon, Bartolo # >> | 33 | 2006 | R | 34 | 7 | 7 | 3 | 2 | 4.61 | .342 | 1.56 | 11.4 | 2.6 | 7.5 | 41.0 | 52 | 24 | 21 | 7 | 12 | 34 | 0 | 0 | 0 | 0 | 4 | 0 | 2 | 4.44 |
| RP | Betancourt, R.Betancourt, Rafael >> | 31 | 2006 | R | 85 | 24 | 0 | 1 | 0 | 2.10 | .285 | 1.17 | 7.9 | 2.6 | 7.9 | 34.1 | 30 | 8 | 8 | 3 | 10 | 30 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 3.35 |
| RP | Mujica, E.Mujica, Edward >> | 22 | 2006 | R | 40 | 22 | 0 | 3 | 2 | 5.40 | .312 | 1.26 | 9.6 | 2.0 | 6.7 | 31.2 | 33 | 23 | 19 | 6 | 7 | 23 | 0 | 5 | 4 | 0 | 0 | 3 | 0 | 5.00 |
| RP | Miller, M.Miller, Matt >> | 35 | 2006 | R | 80 | 10 | 0 | 1 | 0 | 0.00 | .222 | 0.86 | 4.1 | 4.1 | 4.9 | 11.2 | 5 | 0 | 0 | 0 | 5 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.27 |
| RP | Carmona, F.Carmona, Fausto >> | 23 | 2006 | R | 25 | 11 | 0 | 0 | 0 | 6.75 | .409 | 2.02 | 13.8 | 4.8 | 6.4 | 17.1 | 26 | 14 | 13 | 2 | 9 | 12 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.88 |
| SP | Vargas, J.Vargas, Jason >> | 23 | 2006 | L | 12 | 2 | 0 | 1 | 1 | 11.57 | .440 | 2.36 | 13.5 | 11.3 | 11.3 | 4.2 | 6 | 6 | 6 | 2 | 5 | 5 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 10.75 |