| SP | Flaherty, J.Flaherty, Jack >> | 22 | 2018 | R | 95 | 31 | 31 | 11 | 4 | 2.87 | .286 | 1.15 | 7.2 | 3.2 | 9.6 | 182.0 | 145 | 62 | 58 | 22 | 65 | 194 | 0 | 0 | 0 | 0 | 15 | 9 | 6 | 3.66 |
| SP | Wacha, M.Wacha, Michael # >> | 26 | 2018 | R | 77 | 30 | 30 | 9 | 11 | 5.10 | .313 | 1.36 | 8.6 | 3.6 | 8.3 | 173.0 | 166 | 99 | 98 | 18 | 70 | 159 | 0 | 0 | 0 | 0 | 13 | 1 | 0 | 3.75 |
| SP | Martinez, C.Martinez, Carlos # >> | 27 | 2018 | R | 57 | 30 | 30 | 6 | 7 | 5.04 | .348 | 1.57 | 9.2 | 5.0 | 8.4 | 126.2 | 129 | 78 | 71 | 18 | 70 | 118 | 0 | 0 | 0 | 0 | 0 | 4 | 1 | 4.75 |
| SP | Rodriguez, J.Rodriguez, Jefry + >> | 24 | 2018 | R | 38 | 27 | 26 | 7 | 9 | 4.61 | .346 | 1.57 | 9.2 | 5.0 | 7.2 | 113.1 | 115 | 62 | 58 | 13 | 63 | 91 | 0 | 0 | 0 | 0 | 1 | 2 | 3 | 4.61 |
| SP | Wainwright, A.Wainwright, Adam >> | 37 | 2018 | R | 30 | 26 | 19 | 13 | 7 | 3.02 | .294 | 1.24 | 7.3 | 3.9 | 10.3 | 116.1 | 94 | 42 | 39 | 10 | 50 | 133 | 0 | 0 | 0 | 0 | 7 | 1 | 2 | 3.15 |
| CL | Ottavino, A.Ottavino, Adam † >> | 32 | 2018 | R | 97 | 65 | 0 | 5 | 2 | 2.53 | .302 | 1.22 | 5.8 | 5.2 | 9.3 | 64.0 | 41 | 20 | 18 | 5 | 37 | 66 | 0 | 33 | 3 | 0 | 0 | 5 | 2 | 3.92 |
| RP | Poncedeleon, D.Poncedeleon, Daniel † + >> | 26 | 2018 | R | 82 | 70 | 0 | 19 | 0 | 2.85 | .277 | 1.12 | 6.9 | 3.1 | 7.9 | 186.1 | 143 | 61 | 59 | 21 | 65 | 163 | 0 | 8 | 2 | 0 | 0 | 6 | 0 | 3.86 |
| RP | Brebbia, J.Brebbia, John >> | 28 | 2018 | R | 76 | 72 | 0 | 9 | 3 | 2.94 | .280 | 1.14 | 7.8 | 2.5 | 10.5 | 95.0 | 82 | 35 | 31 | 7 | 26 | 111 | 0 | 1 | 5 | 0 | 0 | 3 | 1 | 2.54 |
| RP | Hicks, J.Hicks, Jordan # + >> | 21 | 2018 | R | 61 | 61 | 0 | 2 | 3 | 4.10 | .307 | 1.29 | 6.9 | 4.7 | 8.0 | 74.2 | 57 | 35 | 34 | 9 | 39 | 66 | 0 | 0 | 4 | 0 | 0 | 3 | 5 | 4.50 |
| RP | Hudson, D.Hudson, Dakota + >> | 23 | 2018 | R | 59 | 60 | 0 | 3 | 1 | 3.27 | .309 | 1.33 | 6.7 | 5.3 | 7.9 | 63.1 | 47 | 25 | 23 | 7 | 37 | 55 | 0 | 1 | 2 | 0 | 0 | 1 | 6 | 4.51 |
| RP | Mayers, M.Mayers, Mike + >> | 26 | 2018 | R | 31 | 40 | 0 | 3 | 2 | 3.53 | .290 | 1.18 | 8.0 | 2.7 | 8.6 | 43.1 | 38 | 19 | 17 | 1 | 13 | 41 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 2.44 |