| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 74 | 9 | 9 | 2 | 5 | 4.64 | .305 | 1.30 | 8.6 | 3.1 | 6.1 | 66.0 | 63 | 35 | 34 | 9 | 23 | 45 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 4.50 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 25 | 0 | 0 | 1 | 0.92 | .285 | 1.19 | 5.6 | 5.3 | 9.9 | 29.1 | 18 | 4 | 3 | 1 | 17 | 32 | 0 | 4 | 4 | 0 | 0 | 0 | 2 | 3.00 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 20 | 0 | 1 | 1 | 1.27 | .167 | 0.60 | 4.5 | 1.0 | 10.9 | 28.1 | 14 | 4 | 4 | 1 | 3 | 34 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1.36 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 12 | 0 | 2 | 0 | 2.13 | .269 | 1.11 | 6.8 | 3.8 | 12.0 | 12.2 | 9 | 3 | 3 | 0 | 5 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1.58 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 85 | 9 | 9 | 4 | 4 | 4.92 | .359 | 1.64 | 10.0 | 4.8 | 8.8 | 53.0 | 59 | 31 | 29 | 8 | 28 | 52 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 4.70 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 12 | 0 | 2 | 1 | 1.32 | .293 | 1.17 | 6.2 | 4.8 | 9.0 | 13.2 | 9 | 2 | 2 | 1 | 7 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.85 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 83 | 9 | 9 | 4 | 3 | 3.82 | .303 | 1.27 | 8.2 | 3.3 | 7.5 | 66.0 | 60 | 32 | 28 | 4 | 24 | 55 | 1 | 0 | 0 | 0 | 5 | 2 | 0 | 3.30 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 9 | 9 | 4 | 4 | 2.74 | .247 | 0.97 | 6.9 | 1.8 | 5.9 | 69.0 | 53 | 22 | 21 | 5 | 14 | 45 | 5 | 0 | 0 | 3 | 7 | 1 | 0 | 3.29 |