| SP | Mathewson, C.Mathewson, Christy + $$ >> | 27 | 1908 | R | 90 | 36 | 36 | 16 | 9 | 3.53 | .254 | 1.00 | 7.6 | 1.4 | 4.4 | 252.1 | 214 | 102 | 99 | 28 | 39 | 123 | 12 | 0 | 0 | 4 | 21 | 5 | 1 | 3.99 |
| SP | Santana, J.Santana, Johan $$ >> | 22 | 2004 | L | 86 | 36 | 36 | 15 | 12 | 3.64 | .269 | 1.09 | 7.7 | 2.2 | 7.0 | 230.0 | 196 | 98 | 93 | 27 | 55 | 180 | 6 | 0 | 0 | 0 | 22 | 3 | 4 | 3.72 |
| SP | Joss, A.Joss, Addie # + $$ >> | 21 | 1908 | R | 80 | 35 | 35 | 12 | 13 | 5.21 | .303 | 1.29 | 9.7 | 1.9 | 3.1 | 217.2 | 235 | 131 | 126 | 41 | 46 | 75 | 4 | 0 | 0 | 0 | 14 | 3 | 1 | 5.44 |
| SP | Halladay, R.Halladay, Roy $ >> | 22 | 2011 | R | 36 | 36 | 35 | 8 | 15 | 5.50 | .321 | 1.40 | 10.1 | 2.4 | 5.6 | 162.0 | 182 | 103 | 99 | 25 | 44 | 100 | 6 | 0 | 0 | 1 | 12 | 4 | 2 | 4.66 |
| SP | Matlack, J.Matlack, Jon # $$ >> | 23 | 1974 | L | 33 | 32 | 31 | 8 | 6 | 5.60 | .316 | 1.36 | 9.5 | 2.8 | 4.3 | 154.1 | 162 | 100 | 96 | 21 | 48 | 74 | 2 | 0 | 0 | 1 | 10 | 4 | 1 | 4.82 |
| RP | Konstanty, J.Konstanty, Jim † $$ >> | 30 | 1950 | R | 70 | 76 | 0 | 18 | 3 | 2.71 | .219 | 0.84 | 5.9 | 1.6 | 4.2 | 192.1 | 126 | 63 | 58 | 13 | 35 | 89 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 3.52 |
| RP | Green, C.Green, Chad + $$ >> | 24 | 2021 | R | 68 | 65 | 0 | 5 | 6 | 4.12 | .293 | 1.20 | 8.8 | 2.0 | 6.8 | 98.1 | 96 | 51 | 45 | 20 | 22 | 74 | 0 | 3 | 3 | 0 | 0 | 4 | 3 | 4.94 |
| CL | Kuo, H.Kuo, Hong-Chih † $$ >> | 20 | 2010 | L | 75 | 72 | 0 | 6 | 6 | 2.81 | .261 | 1.03 | 6.0 | 3.3 | 8.5 | 73.2 | 49 | 26 | 23 | 3 | 27 | 69 | 0 | 41 | 5 | 0 | 0 | 2 | 3 | 2.84 |
| RP | Vande Berg, E.Vande Berg, Ed $$ >> | 23 | 1982 | L | 61 | 49 | 0 | 5 | 2 | 2.93 | .243 | 0.93 | 6.5 | 1.9 | 5.2 | 76.2 | 55 | 25 | 25 | 5 | 16 | 44 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 3.45 |
| RP | Niedenfuer, T.Niedenfuer, Tom $$ >> | 24 | 1985 | R | 49 | 42 | 0 | 4 | 1 | 3.47 | .284 | 1.16 | 8.0 | 2.5 | 8.3 | 62.1 | 55 | 25 | 24 | 6 | 17 | 57 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 3.34 |
| RP | Rodriguez, F.Rodriguez, Felix $$ >> | 22 | 2001 | R | 48 | 28 | 0 | 0 | 1 | 3.35 | .247 | 0.96 | 6.1 | 2.7 | 6.6 | 37.2 | 25 | 14 | 14 | 9 | 11 | 27 | 0 | 1 | 0 | 0 | 0 | 1 | 3 | 5.68 |
| SP | Wheeler, Z.Wheeler, Zack >> | 38 | 2021 | R | 44 | 9 | 1 | 2 | 1 | 6.26 | .289 | 1.22 | 9.0 | 2.0 | 7.0 | 23.0 | 23 | 17 | 16 | 7 | 5 | 18 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 6.04 |