| SP | Hamels, C.Hamels, Cole # $ >> | 34 | 2011 | L | 83 | 33 | 33 | 10 | 14 | 5.46 | .306 | 1.30 | 9.5 | 2.2 | 3.8 | 202.2 | 213 | 125 | 123 | 39 | 50 | 86 | 7 | 0 | 0 | 0 | 10 | 5 | 2 | 5.48 |
| SP | Reuschel, R.Reuschel, Rick >> | 25 | 1977 | R | 34 | 24 | 14 | 7 | 9 | 4.59 | .305 | 1.30 | 9.0 | 2.8 | 4.7 | 127.1 | 127 | 70 | 65 | 19 | 39 | 67 | 3 | 1 | 0 | 0 | 7 | 2 | 6 | 4.86 |
| SP | Rusie, A.Rusie, Amos # >> | 36 | 1891 | R | 62 | 32 | 32 | 11 | 9 | 5.30 | .313 | 1.34 | 8.5 | 3.6 | 3.6 | 192.0 | 182 | 121 | 113 | 20 | 76 | 77 | 10 | 0 | 0 | 2 | 12 | 5 | 5 | 4.82 |
| SP | Ryan, N.Ryan, Nolan # $ >> | 24 | 1973 | R | 49 | 31 | 31 | 9 | 17 | 5.11 | .323 | 1.39 | 8.1 | 4.4 | 7.0 | 192.0 | 173 | 119 | 109 | 34 | 94 | 149 | 7 | 0 | 0 | 1 | 12 | 8 | 10 | 5.34 |
| RP | Broxton, J.Broxton, Jonathan $ >> | 32 | 2009 | R | 81 | 51 | 0 | 6 | 2 | 2.75 | .269 | 1.06 | 6.2 | 3.3 | 8.7 | 78.2 | 54 | 27 | 24 | 7 | 29 | 75 | 0 | 14 | 3 | 0 | 0 | 4 | 0 | 3.51 |
| RP | Papelbon, J.Papelbon, Jonathan † $ >> | 29 | 2006 | R | 95 | 60 | 0 | 10 | 2 | 2.74 | .254 | 1.01 | 6.8 | 2.4 | 7.9 | 111.2 | 84 | 37 | 34 | 13 | 29 | 98 | 0 | 3 | 1 | 0 | 0 | 1 | 3 | 3.57 |
| CL | Loaisiga, J.Loaisiga, Jonathan >> | 23 | 2021 | R | 59 | 37 | 0 | 2 | 3 | 4.99 | .274 | 1.13 | 8.1 | 2.3 | 4.1 | 48.2 | 43 | 28 | 27 | 8 | 12 | 22 | 0 | 12 | 1 | 0 | 0 | 0 | 1 | 5.00 |
| RP | Olson, G.Olson, Gregg $ >> | 23 | 1989 | R | 45 | 35 | 0 | 1 | 2 | 2.36 | .255 | 1.01 | 6.2 | 3.0 | 8.2 | 45.2 | 31 | 12 | 12 | 4 | 15 | 41 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 3.40 |
| SP | Sanders, B.Sanders, Ben >> | 35 | 1888 | R | 29 | 15 | 0 | 3 | 3 | 5.54 | .348 | 1.58 | 11.4 | 2.9 | 4.7 | 65.0 | 82 | 47 | 40 | 14 | 21 | 34 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 5.77 |
| SP | Martinez, P.Martinez, Pedro † $ >> | 30 | 2000 | R | 100 | 25 | 24 | 13 | 7 | 3.98 | .246 | 0.96 | 7.4 | 1.2 | 7.7 | 167.1 | 137 | 75 | 74 | 32 | 23 | 142 | 10 | 0 | 0 | 0 | 14 | 4 | 1 | 4.28 |