| SP | Martinez, P.Martinez, Pedro † $$ >> | 36 | 2000 | R | 100 | 35 | 35 | 19 | 7 | 3.06 | .251 | 0.99 | 6.8 | 2.1 | 6.6 | 247.1 | 187 | 87 | 84 | 27 | 57 | 182 | 9 | 0 | 0 | 3 | 21 | 4 | 2 | 3.69 |
| SP | Arrieta, J.Arrieta, Jake † # + $$ >> | 29 | 2015 | R | 99 | 35 | 35 | 18 | 11 | 2.48 | .229 | 0.88 | 6.4 | 1.5 | 6.3 | 261.1 | 186 | 78 | 72 | 22 | 43 | 182 | 14 | 0 | 0 | 2 | 26 | 4 | 7 | 3.24 |
| SP | Scherzer, M.Scherzer, Max † $$ >> | 34 | 2018 | R | 97 | 34 | 34 | 20 | 8 | 2.80 | .253 | 0.98 | 6.5 | 2.3 | 7.7 | 241.0 | 175 | 77 | 75 | 29 | 62 | 206 | 11 | 0 | 0 | 3 | 24 | 8 | 2 | 3.73 |
| SP | Buehler, W.Buehler, Walker $$ >> | 33 | 2021 | R | 95 | 34 | 34 | 17 | 9 | 3.06 | .244 | 0.96 | 6.8 | 1.9 | 7.6 | 253.0 | 190 | 87 | 86 | 22 | 54 | 214 | 14 | 0 | 0 | 6 | 23 | 1 | 6 | 3.09 |
| SP | Cooper, M.Cooper, Mort $$ >> | 25 | 1942 | R | 67 | 34 | 34 | 17 | 11 | 3.86 | .281 | 1.15 | 7.7 | 2.7 | 3.8 | 223.2 | 191 | 99 | 96 | 16 | 67 | 94 | 6 | 0 | 0 | 2 | 18 | 4 | 3 | 4.04 |
| CL | Uehara, K.Uehara, Koji † $$ >> | 26 | 2013 | R | 100 | 68 | 0 | 9 | 6 | 1.75 | .215 | 0.82 | 4.9 | 2.6 | 8.0 | 87.2 | 47 | 17 | 17 | 8 | 25 | 77 | 0 | 45 | 4 | 0 | 0 | 0 | 3 | 3.29 |
| SU | Yates, K.Yates, Kirby $$ >> | 22 | 2024 | R | 99 | 54 | 0 | 0 | 3 | 2.52 | .266 | 1.05 | 5.9 | 3.8 | 8.9 | 60.2 | 39 | 18 | 17 | 7 | 25 | 59 | 0 | 7 | 5 | 0 | 0 | 2 | 0 | 3.90 |
| RP | Davis, W.Davis, Wade $ >> | 31 | 2015 | R | 98 | 53 | 0 | 5 | 3 | 1.99 | .229 | 0.87 | 4.9 | 3.0 | 7.5 | 108.2 | 59 | 24 | 24 | 6 | 36 | 90 | 0 | 3 | 1 | 0 | 0 | 2 | 4 | 3.11 |
| RP | Wilhelmsen, T.Wilhelmsen, Tom # $$ >> | 27 | 2014 | R | 88 | 35 | 0 | 3 | 4 | 5.14 | .306 | 1.29 | 8.0 | 3.5 | 7.4 | 56.0 | 50 | 35 | 32 | 6 | 22 | 46 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 4.04 |
| RP | Sanders, K.Sanders, Ken >> | 25 | 1970 | R | 64 | 24 | 0 | 1 | 2 | 4.11 | .323 | 1.43 | 8.2 | 4.6 | 4.4 | 35.0 | 32 | 20 | 16 | 4 | 18 | 17 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.06 |