| SP | Buehler, W.Buehler, Walker # + $ >> | 30 | 2021 | R | 98 | 16 | 16 | 8 | 6 | 4.40 | .269 | 1.08 | 8.2 | 1.6 | 6.5 | 102.1 | 93 | 50 | 50 | 17 | 18 | 74 | 3 | 0 | 0 | 0 | 9 | 2 | 1 | 4.30 |
| SP | Arrieta, J.Arrieta, Jake $$ >> | 26 | 2015 | R | 98 | 16 | 16 | 8 | 5 | 4.06 | .273 | 1.11 | 7.8 | 2.2 | 5.8 | 102.0 | 88 | 46 | 46 | 21 | 25 | 66 | 4 | 0 | 0 | 2 | 7 | 2 | 1 | 5.18 |
| SP | Fernandez, S.Fernandez, Sid $$ >> | 29 | 1992 | L | 90 | 15 | 15 | 5 | 4 | 5.34 | .293 | 1.22 | 9.2 | 1.9 | 6.3 | 87.2 | 89 | 52 | 52 | 24 | 18 | 61 | 2 | 0 | 0 | 0 | 5 | 2 | 0 | 5.87 |
| SP | Millwood, K.Millwood, Kevin $ >> | 31 | 1999 | R | 91 | 16 | 15 | 9 | 3 | 3.66 | .251 | 0.99 | 7.3 | 1.6 | 5.5 | 103.1 | 84 | 45 | 42 | 12 | 18 | 63 | 6 | 1 | 0 | 1 | 9 | 2 | 3 | 3.87 |
| SP | Dickey, R.Dickey, R.A. >> | 33 | 2012 | R | 69 | 15 | 15 | 8 | 7 | 3.69 | .281 | 1.16 | 7.8 | 2.6 | 5.0 | 107.1 | 93 | 46 | 44 | 11 | 31 | 60 | 5 | 0 | 0 | 1 | 8 | 2 | 0 | 4.14 |
| CL | Betances, D.Betances, Dellin $$ >> | 27 | 2014 | R | 99 | 31 | 0 | 0 | 3 | 2.95 | .210 | 0.80 | 5.6 | 1.7 | 8.4 | 42.2 | 26 | 14 | 14 | 3 | 8 | 39 | 0 | 17 | 2 | 0 | 0 | 0 | 0 | 2.64 |
| SU | Hendriks, L.Hendriks, Liam $$ >> | 31 | 2021 | R | 98 | 26 | 0 | 2 | 0 | 2.40 | .262 | 1.07 | 6.9 | 2.7 | 9.0 | 30.0 | 23 | 8 | 8 | 5 | 9 | 30 | 0 | 3 | 1 | 0 | 0 | 0 | 2 | 4.07 |
| RP | Rivero, F.Rivero, Felipe $ >> | 27 | 2017 | L | 90 | 25 | 0 | 4 | 1 | 2.36 | .220 | 0.81 | 6.4 | 0.9 | 9.2 | 49.2 | 35 | 13 | 13 | 5 | 5 | 50 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 2.71 |
| RP | Hochevar, L.Hochevar, Luke >> | 25 | 2013 | R | 80 | 23 | 0 | 0 | 2 | 3.70 | .263 | 1.07 | 6.8 | 3.0 | 9.8 | 48.2 | 36 | 21 | 20 | 7 | 16 | 52 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.73 |
| RP | Rincon, J.Rincon, Juan >> | 34 | 2004 | R | 70 | 19 | 0 | 1 | 1 | 2.87 | .304 | 1.24 | 7.0 | 4.4 | 9.6 | 31.1 | 24 | 10 | 10 | 5 | 15 | 33 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 4.61 |