| SP | Morton, C.Morton, Charlie $$ >> | 31 | 2021 | R | 100 | 35 | 35 | 15 | 15 | 3.71 | .281 | 1.15 | 8.1 | 2.2 | 6.8 | 247.1 | 223 | 103 | 102 | 34 | 61 | 186 | 10 | 0 | 0 | 1 | 19 | 6 | 6 | 4.10 |
| SP | Arrieta, J.Arrieta, Jake † + $$ >> | 27 | 2015 | R | 98 | 35 | 35 | 23 | 9 | 3.33 | .254 | 1.01 | 7.1 | 2.0 | 5.5 | 259.1 | 205 | 100 | 96 | 30 | 57 | 159 | 10 | 0 | 0 | 3 | 22 | 3 | 7 | 3.97 |
| SP | DeLeon, J.DeLeon, Jose # $$ >> | 31 | 1989 | R | 94 | 34 | 34 | 16 | 13 | 3.14 | .245 | 0.95 | 7.2 | 1.4 | 5.8 | 244.0 | 194 | 88 | 85 | 24 | 39 | 157 | 11 | 0 | 0 | 2 | 22 | 4 | 2 | 3.52 |
| SP | Johnson, W.Johnson, Walter >> | 30 | 1913 | R | 93 | 33 | 33 | 11 | 16 | 2.97 | .250 | 0.97 | 7.1 | 1.7 | 4.7 | 263.2 | 207 | 97 | 87 | 19 | 50 | 136 | 14 | 0 | 0 | 2 | 23 | 7 | 2 | 3.56 |
| CL | Uehara, K.Uehara, Koji † $$ >> | 24 | 2013 | R | 100 | 76 | 0 | 7 | 7 | 2.63 | .248 | 0.98 | 6.6 | 2.3 | 6.8 | 78.2 | 57 | 24 | 23 | 8 | 20 | 59 | 0 | 54 | 5 | 0 | 0 | 1 | 0 | 3.63 |
| SU | Davis, W.Davis, Wade † >> | 29 | 2015 | R | 97 | 65 | 0 | 4 | 6 | 2.07 | .211 | 0.80 | 5.0 | 2.3 | 6.7 | 69.2 | 38 | 16 | 16 | 9 | 18 | 51 | 0 | 45 | 2 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Dotel, O.Dotel, Octavio >> | 26 | 2002 | R | 90 | 57 | 0 | 2 | 2 | 2.14 | .215 | 0.81 | 5.8 | 1.6 | 8.8 | 75.2 | 48 | 18 | 18 | 9 | 13 | 73 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 3.17 |
| RP | Wilhelmsen, T.Wilhelmsen, Tom >> | 25 | 2014 | R | 85 | 34 | 0 | 2 | 4 | 2.82 | .276 | 1.14 | 6.8 | 3.7 | 4.3 | 44.2 | 33 | 15 | 14 | 6 | 18 | 21 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 5.05 |
| RP | Robles, H.Robles, Hansel >> | 27 | 2019 | R | 67 | 21 | 0 | 1 | 0 | 4.40 | .259 | 1.05 | 7.1 | 2.6 | 7.1 | 28.2 | 22 | 14 | 14 | 5 | 8 | 22 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.61 |