| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 99 | 46 | 46 | 15 | 14 | 3.62 | .284 | 1.16 | 7.5 | 3.0 | 9.3 | 303.1 | 252 | 124 | 122 | 40 | 100 | 314 | 4 | 0 | 0 | 1 | 32 | 9 | 6 | 3.72 |
| SP | Lackey, J.Lackey, John >> | 38 | 2016 | R | 82 | 48 | 3 | 11 | 2 | 3.24 | .295 | 1.22 | 7.8 | 3.2 | 7.5 | 175.0 | 151 | 69 | 63 | 21 | 63 | 145 | 0 | 0 | 0 | 0 | 1 | 6 | 5 | 4.09 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 100 | 116 | 0 | 8 | 2 | 2.70 | .252 | 0.98 | 5.6 | 3.3 | 10.3 | 110.0 | 68 | 34 | 33 | 12 | 40 | 126 | 0 | 4 | 5 | 0 | 0 | 3 | 5 | 3.30 |
| RP | Chapman, A.Chapman, Aroldis # >> | 28 | 2016 | L | 99 | 127 | 0 | 3 | 3 | 3.90 | .295 | 1.22 | 7.9 | 3.1 | 8.9 | 67.0 | 59 | 29 | 29 | 10 | 23 | 66 | 0 | 1 | 0 | 0 | 0 | 2 | 3 | 4.09 |
| RP | Reyes, D.Reyes, Dennys >> | 29 | 2006 | L | 89 | 110 | 0 | 1 | 3 | 2.41 | .263 | 1.07 | 6.2 | 3.5 | 7.4 | 52.1 | 36 | 14 | 14 | 4 | 20 | 43 | 0 | 2 | 2 | 0 | 0 | 0 | 4 | 3.50 |
| RP | Rondon, H.Rondon, Hector >> | 28 | 2016 | R | 82 | 50 | 0 | 4 | 3 | 2.45 | .245 | 0.94 | 6.2 | 2.3 | 8.3 | 51.1 | 35 | 14 | 14 | 5 | 13 | 47 | 0 | 9 | 0 | 0 | 0 | 2 | 1 | 3.31 |
| SP | Liriano, F.Liriano, Francisco # >> | 23 | 2006 | L | 91 | 46 | 42 | 2 | 12 | 4.38 | .309 | 1.32 | 8.6 | 3.3 | 8.2 | 150.0 | 143 | 74 | 73 | 21 | 55 | 137 | 0 | 0 | 0 | 0 | 0 | 3 | 9 | 4.15 |