| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 34 | 34 | 12 | 18 | 4.31 | .297 | 1.25 | 9.2 | 2.0 | 4.7 | 244.1 | 250 | 123 | 117 | 29 | 55 | 127 | 9 | 0 | 0 | 0 | 18 | 4 | 4 | 4.23 |
| SP | Leonard, D.Leonard, Dutch † >> | 22 | 1914 | L | 91 | 33 | 33 | 16 | 9 | 3.61 | .299 | 1.25 | 7.7 | 3.5 | 5.0 | 219.1 | 188 | 96 | 88 | 23 | 86 | 121 | 2 | 0 | 0 | 0 | 23 | 6 | 8 | 4.52 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 22 | 22 | 5 | 9 | 5.43 | .326 | 1.45 | 10.0 | 3.1 | 4.7 | 159.0 | 176 | 100 | 96 | 22 | 54 | 83 | 3 | 0 | 0 | 0 | 5 | 1 | 7 | 4.79 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 27 | 22 | 9 | 11 | 5.32 | .324 | 1.39 | 8.1 | 4.5 | 7.1 | 138.2 | 124 | 84 | 82 | 11 | 69 | 109 | 0 | 0 | 0 | 0 | 12 | 6 | 2 | 4.09 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 20 | 20 | 2 | 10 | 5.79 | .350 | 1.62 | 9.3 | 5.3 | 8.3 | 93.1 | 96 | 62 | 60 | 12 | 55 | 86 | 0 | 0 | 0 | 0 | 4 | 0 | 3 | 4.60 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 99 | 0 | 5 | 3 | 2.55 | .285 | 1.18 | 7.4 | 3.3 | 8.6 | 84.2 | 69 | 25 | 24 | 8 | 31 | 80 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 3.48 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 81 | 0 | 1 | 1 | 2.80 | .271 | 1.12 | 7.5 | 2.7 | 7.0 | 54.2 | 45 | 18 | 17 | 3 | 16 | 42 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 3.06 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 53 | 0 | 5 | 2 | 3.25 | .301 | 1.29 | 9.0 | 2.8 | 7.1 | 52.2 | 52 | 23 | 19 | 7 | 16 | 41 | 0 | 7 | 4 | 0 | 0 | 0 | 6 | 4.10 |