| SP | Kluber, C.Kluber, Corey $$ >> | 31 | 2017 | R | 90 | 25 | 25 | 8 | 12 | 5.54 | .312 | 1.34 | 9.4 | 2.7 | 7.9 | 162.1 | 169 | 102 | 100 | 30 | 49 | 142 | 3 | 0 | 0 | 0 | 9 | 3 | 2 | 4.62 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 25 | 25 | 10 | 7 | 4.72 | .316 | 1.35 | 9.0 | 3.1 | 4.4 | 181.0 | 181 | 100 | 95 | 18 | 63 | 88 | 3 | 0 | 0 | 0 | 13 | 7 | 2 | 4.48 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 24 | 24 | 5 | 10 | 5.13 | .327 | 1.45 | 8.7 | 4.4 | 9.5 | 133.1 | 128 | 82 | 76 | 21 | 65 | 141 | 0 | 0 | 0 | 0 | 11 | 1 | 2 | 4.42 |
| RP | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 65 | 0 | 7 | 2 | 2.45 | .289 | 1.20 | 7.3 | 3.5 | 7.6 | 84.1 | 68 | 23 | 23 | 3 | 33 | 71 | 0 | 10 | 4 | 0 | 0 | 2 | 0 | 3.02 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 39 | 0 | 7 | 2 | 4.80 | .328 | 1.47 | 10.0 | 3.2 | 7.0 | 45.0 | 50 | 31 | 24 | 10 | 16 | 35 | 0 | 5 | 4 | 0 | 0 | 0 | 0 | 5.40 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 28 | 0 | 3 | 2 | 5.40 | .365 | 1.73 | 11.8 | 4.2 | 9.7 | 26.2 | 34 | 16 | 16 | 7 | 12 | 28 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 5.73 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 9 | 0 | 1 | 1 | 4.50 | .333 | 1.50 | 7.9 | 5.6 | 10.1 | 8.0 | 7 | 4 | 4 | 0 | 5 | 9 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.63 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 10 | 0 | 1 | 1 | 2.13 | .224 | 0.87 | 6.8 | 1.5 | 12.8 | 12.2 | 9 | 3 | 3 | 3 | 2 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.92 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 13 | 0 | 0 | 0 | 3.63 | .257 | 1.04 | 5.8 | 3.7 | 8.5 | 17.1 | 11 | 7 | 7 | 2 | 7 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.88 |