| SP | McNally, D.McNally, Dave # >> | 26 | 1968 | L | 96 | 32 | 32 | 14 | 11 | 3.66 | .304 | 1.29 | 8.7 | 3.0 | 5.9 | 240.2 | 231 | 107 | 98 | 24 | 80 | 158 | 13 | 0 | 0 | 5 | 19 | 4 | 5 | 4.03 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 32 | 32 | 14 | 13 | 5.08 | .320 | 1.38 | 9.8 | 2.6 | 4.7 | 221.1 | 241 | 129 | 125 | 26 | 64 | 116 | 5 | 0 | 0 | 2 | 15 | 8 | 1 | 4.46 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 31 | 31 | 13 | 12 | 5.27 | .349 | 1.58 | 10.6 | 3.7 | 4.6 | 201.2 | 236 | 126 | 118 | 23 | 82 | 103 | 4 | 0 | 0 | 1 | 16 | 6 | 9 | 4.78 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 30 | 30 | 11 | 12 | 4.48 | .326 | 1.44 | 7.6 | 5.4 | 4.6 | 198.2 | 168 | 113 | 99 | 21 | 118 | 101 | 1 | 0 | 0 | 0 | 17 | 2 | 2 | 5.18 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 75 | 0 | 6 | 1 | 3.66 | .289 | 1.19 | 7.5 | 3.3 | 8.8 | 115.2 | 96 | 47 | 47 | 13 | 42 | 112 | 0 | 6 | 2 | 0 | 0 | 3 | 0 | 3.70 |
| RP | Devine, J.Devine, Joey # >> | 25 | 2008 | R | 82 | 63 | 0 | 5 | 4 | 5.63 | .301 | 1.28 | 7.9 | 3.6 | 8.1 | 72.0 | 63 | 45 | 45 | 11 | 29 | 65 | 0 | 9 | 3 | 0 | 0 | 1 | 0 | 4.43 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 54 | 0 | 5 | 0 | 3.69 | .304 | 1.30 | 8.9 | 2.8 | 6.5 | 61.0 | 60 | 26 | 25 | 7 | 19 | 44 | 0 | 6 | 3 | 0 | 0 | 1 | 2 | 4.03 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 44 | 0 | 2 | 2 | 4.59 | .293 | 1.22 | 7.7 | 3.3 | 8.4 | 49.0 | 42 | 29 | 25 | 7 | 18 | 46 | 0 | 3 | 1 | 0 | 0 | 1 | 4 | 4.14 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 50 | 1 | 0 | 0 | 1 | 5.40 | .412 | 1.80 | 12.0 | 6.0 | 9.0 | 3.1 | 4 | 2 | 2 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.00 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 25 | 0 | 3 | 5 | 6.41 | .395 | 1.93 | 13.4 | 4.2 | 6.5 | 39.1 | 58 | 28 | 28 | 3 | 18 | 28 | 0 | 2 | 1 | 0 | 0 | 1 | 2 | 4.03 |