| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 35 | 35 | 14 | 15 | 4.44 | .308 | 1.30 | 8.4 | 3.3 | 8.1 | 223.0 | 209 | 119 | 110 | 26 | 82 | 201 | 1 | 0 | 0 | 0 | 18 | 7 | 1 | 3.91 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 33 | 33 | 12 | 13 | 4.08 | .310 | 1.31 | 8.5 | 3.3 | 7.1 | 216.1 | 204 | 103 | 98 | 23 | 79 | 171 | 4 | 0 | 0 | 3 | 18 | 8 | 1 | 4.01 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 32 | 32 | 10 | 10 | 2.76 | .265 | 1.05 | 7.0 | 2.4 | 5.1 | 228.2 | 177 | 77 | 70 | 16 | 62 | 128 | 4 | 0 | 0 | 1 | 26 | 8 | 3 | 3.71 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 107 | 0 | 3 | 2 | 2.61 | .272 | 1.08 | 6.6 | 3.1 | 9.3 | 72.1 | 53 | 22 | 21 | 5 | 25 | 74 | 0 | 5 | 2 | 0 | 0 | 3 | 2 | 3.01 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 74 | 0 | 3 | 3 | 3.89 | .311 | 1.30 | 8.3 | 3.4 | 9.7 | 37.0 | 34 | 16 | 16 | 1 | 14 | 40 | 0 | 4 | 1 | 0 | 0 | 2 | 3 | 2.49 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 90 | 0 | 4 | 2 | 2.64 | .246 | 0.95 | 6.0 | 2.7 | 6.2 | 71.2 | 47 | 21 | 21 | 4 | 21 | 49 | 0 | 8 | 0 | 0 | 0 | 2 | 4 | 3.32 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 70 | 0 | 6 | 6 | 3.46 | .257 | 1.02 | 7.8 | 1.4 | 7.4 | 52.0 | 45 | 21 | 20 | 8 | 8 | 43 | 0 | 8 | 5 | 0 | 0 | 1 | 0 | 3.87 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 59 | 0 | 0 | 4 | 4.97 | .298 | 1.22 | 7.7 | 3.5 | 10.5 | 41.2 | 35 | 23 | 23 | 8 | 16 | 48 | 0 | 6 | 3 | 0 | 0 | 2 | 1 | 4.51 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 12 | 1 | 0 | 0 | 2.04 | .254 | 1.00 | 6.1 | 2.9 | 9.3 | 53.0 | 36 | 13 | 12 | 5 | 17 | 55 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 3.17 |